Phorbol

Phorbol

SCHEMBL417521

CC1=C[C@H]2[C@@]3(O)[C@H](C)[C@@H](O)[C@]4(O)[C@H]([C@@H]3C=C(CO)C[C@]2(O)C1=O)C4(C)C.CCCCCCCCCCCCCC(=O)OC(C)=O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 5/20 0.69
PRKCG P05129 5/20 0.69
PRKD3 O94806 4/20 0.69
PRKCB P05771 4/20 0.69
PRKCH P24723 4/20 0.69
PRKCI P41743 4/20 0.69
PRKCE Q02156 4/20 0.69
PRKCQ Q04759 4/20 0.69
PRKCZ Q05513 4/20 0.69
PRKCD Q05655 4/20 0.69
PRKD1 Q15139 4/20 0.69
USP2 O75604 2/20 0.69
TP53 P04637 2/20 0.69
KDM4E B2RXH2 1/20 0.69
ALDH1A1 P00352 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
CYP3A4 P08684 1/20 0.69
CYP2C9 P11712 1/20 0.69
TSHR P16473 1/20 0.69
NFKB1 P19838 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phorbol SCHEMBL20582541 1.00 PRKCA (0.69) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL10620832 1.00 PRKCA (0.69) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL27616694 1.00 PRKCA (0.69) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL1893791 1.00 PRKCA (0.69) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL27579226 0.96 PRKCA (0.67) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL21462215 0.92 PRKCA (0.66) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL5904049 0.92 PRKCA (0.60) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL27299282 0.90 PRKCA (0.63) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL7615331 0.90 PRKCA (0.62) PRKCAPRKCGPRKD3PRKCBPRKCH
Phorbol SCHEMBL64353 0.90 PRKCA (0.62) PRKCAPRKCGPRKD3PRKCBPRKCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1903 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119931934-A High-purity peripheral blood source tool B lymphocyte culture system and method 复旦大学附属中山医院 2025-05-06 CN claimed
US-20240301092-A1 HEPARIN FROM MODIFIED MST CELLS AND METHODS OF MAKING AND USING TEGA THERAPEUTICS, INC. 2024-09-12 US claimed
CN-117904045-A High-purity peripheral blood source tool B lymphocyte culture system and method 复旦大学附属中山医院 2024-04-19 CN claimed
WO-2023278631-A1 HEPARIN FROM MODIFIED MST CELLS AND METHODS OF MAKING AND USING TEGA THERAPEUTICS, INC. (US) 2023-01-05 WO claimed
US-20220305049-A1 HEPARIN AND HEPARAN SULFATE FROM MODIFIED MST CELLS AND METHODS OF MAKING AND USING TEGA THERAPEUTICS, INC. 2022-09-29 US claimed
EP-4021461-A1 HEPARIN AND HEPARAN SULFATE FROM MODIFIED MST CELLS AND METHODS OF MAKING AND USING Tega Therapeutics, Inc. (US) 2022-07-06 EP claimed
CN-113686830-B Batch semi-channel function level detection method based on fluorescent dye uptake 中国环境科学研究院 2022-05-20 CN claimed
CN-113686830-A Batch semi-channel function level detection method based on fluorescent dye uptake 中国环境科学研究院 2021-11-23 CN claimed
WO-2021041711-A1 HEPARIN AND HEPARAN SULFATE FROM MODIFIED MST CELLS AND METHODS OF MAKING AND USING TEGA THERAPEUTICS, INC. (US) 2021-03-04 WO claimed
US-20200338125-A1 METHOD FOR EXPANSION OF LYMPHOCYTES LUDWIG INSTITUTE FOR CANCER RESEARCH LTD (CH) 2020-10-29 US claimed
US-20020160415-A1 Methods, pharmaceutical formulations and kits for identification of subjects at risk for cancer and for the prevention of cancer in at- risk subjects ENDACEA, INC. 2002-10-31 US claimed
WO-2000070341-A9 METHODS, PHARMACEUTICAL FORMULATIONS AND KITS FOR IDENTIFICATION OF SUBJECTS AT RISK FOR CANCER LINK TECHNOLOGY INC (US) 2002-04-18 WO claimed
EP-1180239-A2 METHODS, PHARMACEUTICAL FORMULATIONS AND KITS FOR IDENTIFICATION OF SUBJECTS AT RISK FOR CANCER Link Technology, Inc. (US) 2002-02-20 EP claimed
EP-1043928-A4 METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING TUMORS USING ADENOSINE RECEPTOR ACTIVATED CELLS LINK TECHNOLOGY INC (US) 2001-01-17 EP claimed
US-6159701-A Method and compositions for treating and diagnosing tumors using adenosine receptor activated cells LINK TECHNOLOGY INCORPORATED (US) 2000-12-12 US claimed
EP-1054954-A1 DEVELOPMENT OF REGULATORY CELLS AS A MEANS FOR TREATING AUTOIMMUNE DISEASE HEMOSOL INC. (CA) 2000-11-29 EP claimed
WO-2000070341-A2 METHODS, PHARMACEUTICAL FORMULATIONS AND KITS FOR IDENTIFICATION OF SUBJECTS AT RISK FOR CANCER LINK TECHNOLOGY, INC. (US) 2000-11-23 WO claimed
EP-1043928-A1 METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING TUMORS USING ADENOSINE RECEPTOR ACTIVATED CELLS Link Technology, Inc. (US) 2000-10-18 EP claimed
WO-1999038953-A1 DEVELOPMENT OF REGULATORY CELLS AS A MEANS FOR TREATING AUTOIMMUNE DISEASE HEMOSOL INC. (CA) 1999-08-05 WO claimed
WO-1998019541-A1 METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING TUMORS USING ADENOSINE RECEPTOR ACTIVATED CELLS LINK TECHNOLOGY, INC. (US) 1998-05-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240301092-A1 HEPARIN FROM MODIFIED MST CELLS AND METHODS OF MAKING AND USING MST1, MST1R, HPSE PRKCA 2076/4885PRKCG 2228/4885PRKD3 1834/4885
US-20220305049-A1 HEPARIN AND HEPARAN SULFATE FROM MODIFIED MST CELLS AND METHODS OF MAKING AND USING MST1, HPSE, MST1R PRKCA 2341/4885PRKCG 2519/4885PRKD3 1818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.