Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.60 |
| ▸ | PRKCG | P05129 | 5/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.60 |
| ▸ | PRKCB | P05771 | 4/20 | 0.60 |
| ▸ | PRKCH | P24723 | 4/20 | 0.60 |
| ▸ | PRKCI | P41743 | 4/20 | 0.60 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.60 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.60 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.60 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phorbol SCHEMBL10620832 | 0.92 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL417521 | 0.92 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL1893791 | 0.92 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27616694 | 0.92 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL20582541 | 0.92 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27579226 | 0.88 | PRKCA (0.67) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL21462215 | 0.84 | PRKCA (0.66) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27299282 | 0.82 | PRKCA (0.63) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL7615331 | 0.82 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL64353 | 0.82 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716558-B2 | Method of altering glycosylation of proteins in response to nojirimycin glucuronide in a plant cell expressing glucuronidase | MARKER GENE TECHNOLOGIES, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20060105915-A1 | Compositions and methods for targeted enzymatic release of cell regulatory compounds | MARKER GENE TECHNOLOGIES, INC. | 2006-05-18 | — | — | US | disclosed |
| US-20040101932-A1 | Compositions and methods for targeted enzymatic release of cell regulatory compounds | MARKER GENE TECHNOLOGIES, INC. | 2004-05-27 | — | — | US | disclosed |
| US-6656917-B1 | Enzyme encoded by vector recognizes and binds to the inactive conjugate, and releases the bioactive compound from conjugation in an amount effective to enhance growth | MARKER GENE TECHNOLOGIES, INC. | 2003-12-02 | — | — | US | disclosed |
| EP-1200131-A2 | COMPOSITIONS AND METHODS FOR TARGETED ENZYMATIC RELEASE OF CELL REGULATORY COMPOUNDS | Marker Gene Technologies, Inc. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001002020-A2 | COMPOSITIONS AND METHODS FOR TARGETED ENZYMATIC RELEASE OF CELL REGULATORY COMPOUNDS | MARKER GENE TECHNOLOGIES, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040101932-A1 | Compositions and methods for targeted enzymatic release of cell regulatory compounds | GUSB, PREP, PEPD | PRKCA 2370/4885PRKCG 1803/4885PRKD3 2239/4885 |
| US-20060105915-A1 | Compositions and methods for targeted enzymatic release of cell regulatory compounds | GUSB, PREP, PEPD | PRKCA 2370/4885PRKCG 1803/4885PRKD3 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.