Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109103 | 0.81 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL600415 | 0.81 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| Hydrochloric Acid SCHEMBL7492690 | 0.78 | NOTUM (0.57) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| Hydrochloric Acid SCHEMBL7492685 | 0.78 | NOTUM (0.57) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL30546903 | 0.78 | NOTUM (0.49) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL3397331 | 0.78 | NOTUM (0.56) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL5803359 | 0.77 | SLC22A12 (0.45) | TSHRCYP3A4CHRNB2CHRNA4NPSR1 | |
| SCHEMBL7169526 | 0.77 | NOTUM (0.56) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL7162130 | 0.77 | L3MBTL1 (0.53) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL4630338 | 0.77 | CYP3A4 (0.44) | NOTUMTSHRRAB9AL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632956-B2 | Fragrance ingredients, applications, compositions and methods | GIVAUDAN SA (CH) | 2009-12-15 | — | — | US | claimed |
| US-20090036690-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2009-02-05 | — | — | US | claimed |
| EP-1799797-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-05-14 | — | — | EP | claimed |
| EP-1799797-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2007-06-27 | — | — | EP | claimed |
| WO-2006039822-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2006-04-20 | — | — | WO | claimed |
| US-7632956-B2 | Fragrance ingredients, applications, compositions and methods | GIVAUDAN SA (CH) | 2009-12-15 | — | — | US | disclosed |
| US-7632956-B2 | Fragrance ingredients, applications, compositions and methods | GIVAUDAN SA (CH) | 2009-12-15 | — | — | US | disclosed |
| US-7632956-B2 | Fragrance ingredients, applications, compositions and methods | GIVAUDAN SA (CH) | 2009-12-15 | — | — | US | disclosed |
| US-20090036690-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2009-02-05 | — | — | US | disclosed |
| US-20090036690-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2009-02-05 | — | — | US | disclosed |
| US-20090036690-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2009-02-05 | — | — | US | disclosed |
| EP-1799797-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-05-14 | — | — | EP | disclosed |
| EP-1799797-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-05-14 | — | — | EP | disclosed |
| EP-1799797-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006039822-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2006-04-20 | — | — | WO | disclosed |
| US-6566533-B1 | Reacting aza-heterocyclic compounds (indoles and carbazoles) with alkyl- or aryl-halides in the presence of carbon dioxide and alkali carbonate | WARNER-LAMBERT COMPANY LLC | 2003-05-20 | — | — | US | disclosed |
| EP-1165511-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058286-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | Gödecke GmbH (DE) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036690-A1 | ORGANIC COMPOUNDS | TRPA1, IDO1, INMT | NOTUM 68/4885TSHR 3438/4885RAB9A 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.