Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | EPOR | P19235 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415524 | 0.89 | CCR6 (0.48) | ALDH1A1MAPK1L3MBTL1CCR6PAX8 | |
| SCHEMBL415196 | 0.82 | LTA4H (0.45) | ALDH1A1L3MBTL1CCR6PAX8LTA4H | |
| SCHEMBL417987 | 0.80 | CCR6 (0.46) | ALDH1A1MAPK1L3MBTL1CCR6PAX8 | |
| SCHEMBL27463329 | 0.79 | LMNA (0.38) | ALDH1A1MAPK1L3MBTL1CCR6PAX8 | |
| SCHEMBL1240675 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1LTA4HKMT2A | |
| SCHEMBL22273544 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1SLC15A1MEN1 | |
| SCHEMBL4920576 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1LTA4HKMT2A | |
| Hydrochloric Acid SCHEMBL5969292 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1LTA4HKMT2A | |
| SCHEMBL23535912 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1CCR6PAX8 | |
| SCHEMBL23975173 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664409-B2 | Process for the preparation of (poly) aminoalkylaminoacetamide derivatives of epipodophyllotoxin useful for their applications in therapeutics as anticancer agent | PIERRE FABRE MEDICAMENT (FR) | 2014-03-04 | — | — | US | disclosed |
| US-20120022273-A1 | PROCESS FOR THE PREPARATION OF (POLY) AMINOALKYLAMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN USEFUL FOR THEIR APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENT | PIERRE FABRE MEDICAMENT (FR) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022273-A1 | PROCESS FOR THE PREPARATION OF (POLY) AMINOALKYLAMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN USEFUL FOR THEIR APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENT | PTMA, NPEPPS, DNPEP | ALDH1A1 4168/4885MAPK1 4605/4885L3MBTL1 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.