Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326021 | 0.79 | ALDH1A1 (0.47) | TSHRLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL4187378 | 0.76 | KDM4E (0.51) | TSHRLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL4347955 | 0.72 | TEAD1 (0.41) | TSHRLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL4738274 | 0.67 | MAPT (0.45) | TSHRLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL934157 | 0.66 | TSHR (0.54) | TSHRLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL4734032 | 0.64 | MAPT (0.47) | TSHRLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL4187568 | 0.64 | ALDH1A1 (0.47) | TSHRLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL4749247 | 0.63 | MAPT (0.48) | TSHRLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL11564640 | 0.63 | LMNA (0.51) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL933087 | 0.62 | NPSR1 (0.52) | TSHRLMNAMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | claimed |
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | disclosed |