Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751445 | 0.89 | L3MBTL1 (0.58) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4749283 | 0.81 | MAPT (0.45) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4749651 | 0.76 | KDM4E (0.54) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4783860 | 0.75 | MAPT (0.48) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL934157 | 0.72 | TSHR (0.54) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4738274 | 0.72 | MAPT (0.45) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL11564640 | 0.72 | LMNA (0.51) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4749265 | 0.72 | ALDH1A1 (0.58) | MAPTLMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL4743665 | 0.70 | KMT2A (0.73) | MAPTLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL4735942 | 0.70 | HTT (0.52) | MAPTTDP1LMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |