Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.44 |
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171002 | 0.88 | CTSL (0.49) | CTSSCTSKCTSLCTSB | |
| SCHEMBL13854085 | 0.87 | RORC (0.45) | MAPK1RORC | |
| SCHEMBL4191772 | 0.85 | ATM (0.40) | MAPK1 | |
| SCHEMBL4190119 | 0.85 | ATM (0.40) | MAPK1 | |
| SCHEMBL4186154 | 0.85 | CTSS (0.42) | CTSSCTSKCTSLCTSB | |
| Hydrochloric Acid SCHEMBL4189192 | 0.83 | ATM (0.40) | CTSSMAPK1 | |
| SCHEMBL4185698 | 0.82 | KMT2A (0.40) | CTSSCTSKCTSLCTSBRORC | |
| SCHEMBL4185942 | 0.82 | CTSK (0.48) | CTSSCTSKCTSB | |
| SCHEMBL4183416 | 0.82 | CTSK (0.48) | CTSSCTSKCTSB | |
| SCHEMBL4188439 | 0.82 | CTSK (0.48) | CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124619-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-05-14 | — | — | US | disclosed |
| US-20090124619-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124619-A1 | NOVEL COMPOUNDS | TRPV4, TRPC4, TRPV1 | CTSS 1717/4885CTSK 1738/4885CTSL 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.