Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506563 | 0.79 | CYP3A4 (0.38) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL8506068 | 0.77 | CHRM2 (0.44) | CYP2D6HTR1ADRD2ALDH1A1CHRM2 | |
| SCHEMBL7675371 | 0.74 | LMNA (0.54) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL7675246 | 0.71 | LMNA (0.54) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL7679060 | 0.71 | LMNA (0.57) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL8507603 | 0.70 | LMNA (0.64) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL8506196 | 0.70 | LMNA (0.39) | LMNACYP2D6HTR1ADRD2SLC6A2 | |
| SCHEMBL11252431 | 0.69 | LMNA (1.00) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL19505755 | 0.68 | MAPK1 (0.40) | LMNAHTR1ADRD2CHRM2CHRM4 | |
| SCHEMBL25066219 | 0.68 | LMNA (0.91) | LMNACYP2D6MAPTHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9326934-B2 | Drug delivery from rapid gelling polymer composition | ANGIOTECH INTERNATIONAL AG | 2016-05-03 | — | — | US | disclosed |
| US-20120252905-A1 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | ANGIOTECH INTERNATIONAL AG | 2012-10-04 | — | — | US | disclosed |
| US-20090192214-A1 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | ANGIOTECH INTERNATIONAL AG (CH) | 2009-07-30 | — | — | US | disclosed |
| EP-0733035-B1 | TRICYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORP (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0733035-A1 | TRICYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5538986-A | INHIBITORS OF TUMOR NECROSIS FACTOR-ALPHA, DIBENZOCYCLOHEPTANE AND DIBENZOXEPINE DERIVATIVES | SCHERING CORPORATION (US) | 1996-07-23 | — | — | US | disclosed |
| WO-1995015939-A1 | TRICYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252905-A1 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | PGF, VCAM1, COL14A1 | LMNA 1945/4885CYP2D6 1593/4885MAPT 2217/4885 |
| US-20090192214-A1 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | PGF, VCAM1, COL14A1 | LMNA 1945/4885CYP2D6 1593/4885MAPT 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.