Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101046 | 0.80 | ACHE (0.58) | ACHEPTPN1PTAFRMEN1KMT2A | |
| SCHEMBL4171458 | 0.76 | BCHE (0.40) | PTAFRKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8886677 | 0.75 | ACHE (0.43) | ACHEPTPN1PTAFRHTR2AHTR2C | |
| SCHEMBL13414990 | 0.74 | ACHE (0.54) | ACHEPTPN1PTAFRMEN1KMT2A | |
| SCHEMBL4185456 | 0.73 | FDPS (0.51) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8885280 | 0.70 | ACHE (0.46) | ACHEPTPN1PTAFRMEN1KMT2A | |
| SCHEMBL31445795 | 0.67 | HTR2A (0.55) | ACHEHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL8886456 | 0.67 | FPR2 (0.45) | ACHEPTPN1PTAFRMEN1KMT2A | |
| SCHEMBL5783392 | 0.66 | PTPN1 (0.40) | ACHEPTPN1PTAFRMEN1KMT2A | |
| SCHEMBL7814590 | 0.65 | ACHE (0.44) | ACHEPTPN1PTAFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130004430-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | BREMER CHRISTOPH (DE) | 2013-01-03 | — | — | US | disclosed |
| US-8212058-B2 | Fluorescent photoprobe for the imaging of endothelin receptors | Universitatskilinikum Munster (DE) | 2012-07-03 | — | — | US | disclosed |
| US-20090169483-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | UNIVERSITATSKLINIKUM MUNSTER (DE) | 2009-07-02 | — | — | US | disclosed |
| EP-1931392-A2 | A FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | Universitätsklinikum Münster (DE) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007028599-A2 | A FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | Universitätsklinikum Münster (DE) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169483-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | EDNRB, EDNRA, ECE1 | ACHE 3039/4885PTPN1 3511/4885PTAFR 78/4885 |
| US-20130004430-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | EDNRB, EDNRA, ECE1 | ACHE 3061/4885PTPN1 3524/4885PTAFR 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.