Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | PTAFR | P25105 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183391 | 0.81 | ADRB2 (0.42) | BCHECNR2ADRB2HTR1ASUCNR1 | |
| SCHEMBL4178653 | 0.76 | ACHE (0.40) | PTAFRKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7263013 | 0.75 | BCHE (0.43) | BCHECNR2ADRB2HTR1ASUCNR1 | |
| SCHEMBL29962406 | 0.72 | BCHE (0.44) | BCHECNR2ADRB2HTR1ASUCNR1 | |
| SCHEMBL1667818 | 0.72 | BCHE (0.44) | BCHECNR2ADRB2HTR1ASUCNR1 | |
| SCHEMBL1667842 | 0.72 | BCHE (0.44) | BCHECNR2ADRB2HTR1ASUCNR1 | |
| SCHEMBL13883179 | 0.71 | BCHE (0.47) | BCHECNR2ADRB2HTR1ASUCNR1 | |
| SCHEMBL12522223 | 0.70 | KDM4E (0.43) | BCHECNR2ADRB2HTR1ASUCNR1 | |
| SCHEMBL18544320 | 0.70 | FDPS (0.59) | KMT2AKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11101046 | 0.70 | ACHE (0.58) | PTAFRKMT2AKDM4EALDH1A1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130004430-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | BREMER CHRISTOPH (DE) | 2013-01-03 | — | — | US | disclosed |
| US-8212058-B2 | Fluorescent photoprobe for the imaging of endothelin receptors | Universitatskilinikum Munster (DE) | 2012-07-03 | — | — | US | disclosed |
| US-20090169483-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | UNIVERSITATSKLINIKUM MUNSTER (DE) | 2009-07-02 | — | — | US | disclosed |
| EP-1931392-A2 | A FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | Universitätsklinikum Münster (DE) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007028599-A2 | A FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | Universitätsklinikum Münster (DE) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169483-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | EDNRB, EDNRA, ECE1 | BCHE 2453/4885CNR2 218/4885PTAFR 78/4885 |
| US-20130004430-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | EDNRB, EDNRA, ECE1 | BCHE 2452/4885CNR2 222/4885PTAFR 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.