Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13743051 | 0.89 | NAMPT (0.46) | NAMPTSMN1; SMN2HTTKDM4EHPGD | |
| SCHEMBL13743157 | 0.88 | KDM4E (0.45) | GBA1NAMPTHTTKDM4EHPGD | |
| SCHEMBL13743048 | 0.87 | SMN1; SMN2 (0.48) | GBA1HIF1ANAMPTPDE10ASMN1; SMN2 | |
| SCHEMBL4183360 | 0.87 | ALDH1A1 (0.48) | NAMPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL13743477 | 0.85 | NAMPT (0.45) | NAMPTSMN1; SMN2KDM4EHPGDJAK3 | |
| SCHEMBL13743494 | 0.85 | NAMPT (0.43) | GBA1NAMPTSMN1; SMN2HTTKDM4E | |
| SCHEMBL4181449 | 0.83 | GBA1 (0.46) | GBA1NAMPTHTTKMT2AKDM4E | |
| SCHEMBL4178991 | 0.81 | NAMPT (0.40) | GBA1HIF1ANAMPTPDE10ASMN1; SMN2 | |
| SCHEMBL4176021 | 0.81 | PDE10A (0.40) | GBA1HIF1ANAMPTPDE10ASMN1; SMN2 | |
| SCHEMBL4185586 | 0.79 | GBA1 (0.39) | GBA1HIF1ANAMPTPDE10AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | MYLK, MYH2, MYH10 | GBA1 3801/4885HIF1A 3543/4885NAMPT 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.