Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FOS | P01100 | 8/20 | 0.45 |
| ▸ | JUN | P05412 | 8/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 8/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 8/20 | 0.45 |
| ▸ | RELA | Q04206 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183055 | 0.87 | GBA1 (0.45) | KDM4EMEN1HTTKMT2ANPSR1 | |
| SCHEMBL13743048 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMEN1HTTKMT2A | |
| SCHEMBL13743477 | 0.84 | NAMPT (0.45) | KDM4EMAPK1ALOX15SMN1; SMN2NPC1 | |
| SCHEMBL13743051 | 0.84 | NAMPT (0.46) | ALDH1A1KDM4ELMNATP53HTT | |
| SCHEMBL13743157 | 0.81 | KDM4E (0.45) | ALDH1A1KDM4ELMNAMAPK1TP53 | |
| SCHEMBL13743494 | 0.80 | NAMPT (0.43) | ALDH1A1KDM4ELMNAMAPK1TP53 | |
| SCHEMBL4181449 | 0.79 | GBA1 (0.46) | ALDH1A1KDM4ETSHRHTTKMT2A | |
| SCHEMBL4176021 | 0.78 | PDE10A (0.40) | ALDH1A1KDM4EMEN1HTTKMT2A | |
| SCHEMBL4176455 | 0.78 | PGK1 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13743133 | 0.77 | KDM4E (0.46) | ALDH1A1MAPTKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | MYLK, MYH2, MYH10 | ALDH1A1 1710/4885MAPT 530/4885KDM4E 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.