Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183066 | 0.93 | CYP3A4 (0.39) | POLBGBA1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL4183367 | 0.89 | CYP2C19 (0.37) | POLBGBA1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL4185956 | 0.85 | POLB (0.35) | POLBGBA1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL4185582 | 0.85 | GBA1 (0.39) | GBA1CYP1A2ALDH1A1MAPK1LMNA | |
| SCHEMBL4179058 | 0.82 | GBA1 (0.40) | GBA1CYP1A2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL4184002 | 0.79 | GBA1 (0.43) | GBA1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL13743367 | 0.78 | FLT3 (0.45) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2JAK3 | |
| SCHEMBL4178985 | 0.77 | GBA1 (0.39) | POLBGBA1CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL4183379 | 0.76 | STAT6 (0.38) | POLBGBA1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL13743392 | 0.73 | LMNA (0.44) | POLBGBA1CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | MYLK, MYH2, MYH10 | POLB 2180/4885GBA1 3801/4885CYP1A2 1639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.