Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 11/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631974 | 0.85 | ROCK2 (0.48) | CSNK2A2CSNK2A1GBA1ROCK2ROCK1 | |
| SCHEMBL1630222 | 0.85 | ROCK2 (0.45) | CSNK2A2CSNK2A1GBA1ROCK2ROCK1 | |
| SCHEMBL13743506 | 0.84 | GBA1 (0.49) | CSNK2A2CSNK2A1GBA1ROCK2ROCK1 | |
| SCHEMBL4185596 | 0.84 | ROCK2 (0.47) | GBA1ROCK2ROCK1KDM4EMEN1 | |
| SCHEMBL4188524 | 0.79 | CSNK2A2 (0.51) | CSNK2A2CSNK2A1GBA1KDM4EMEN1 | |
| SCHEMBL4179070 | 0.79 | ROCK2 (0.41) | CSNK2A2CSNK2A1GBA1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL4178767 | 0.79 | CSNK2A2 (0.50) | CSNK2A2CSNK2A1GBA1KDM4EMEN1 | |
| SCHEMBL4186002 | 0.78 | GBA1 (0.46) | CSNK2A2CSNK2A1GBA1ROCK2ROCK1 | |
| SCHEMBL4185997 | 0.75 | GBA1 (0.46) | CSNK2A2CSNK2A1GBA1ROCK2ROCK1 | |
| SCHEMBL4179062 | 0.74 | KDM4E (0.43) | CSNK2A2CSNK2A1GBA1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | MYLK, MYH2, MYH10 | CSNK2A2 534/4885CSNK2A1 714/4885GBA1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.