Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544320 | 0.87 | FDPS (0.59) | FDPSALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL18570044 | 0.84 | CA12 (0.46) | ADRB2HTR1ACYP2D6CYP2C19KMT2A | |
| SCHEMBL24266997 | 0.82 | L3MBTL1 (0.42) | ALDH1A1MAPTHPGDCYP2D6CYP2C19 | |
| SCHEMBL23318482 | 0.81 | ALDH1A1 (0.49) | ADRB2HTR1ABCHECNR2FDPS | |
| SCHEMBL18553857 | 0.81 | CA12 (0.41) | FDPSALDH1A1CYP2D6CYP2C19KMT2A | |
| SCHEMBL25815655 | 0.81 | BCHE (0.43) | ADRB2HTR1ABCHECNR2CYP2D6 | |
| SCHEMBL4171458 | 0.81 | BCHE (0.40) | ADRB2HTR1ABCHECNR2ALDH1A1 | |
| SCHEMBL18544346 | 0.80 | FDPS (0.60) | FDPSALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL18569874 | 0.80 | CA12 (0.43) | ADRB2HTR1AALDH1A1MAPTCYP2D6 | |
| SCHEMBL24838619 | 0.79 | ADRB2 (0.45) | ADRB2HTR1ABCHECNR2FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130004430-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | BREMER CHRISTOPH (DE) | 2013-01-03 | — | — | US | disclosed |
| US-8212058-B2 | Fluorescent photoprobe for the imaging of endothelin receptors | Universitatskilinikum Munster (DE) | 2012-07-03 | — | — | US | disclosed |
| US-20090169483-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | UNIVERSITATSKLINIKUM MUNSTER (DE) | 2009-07-02 | — | — | US | disclosed |
| EP-1931392-A2 | A FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | Universitätsklinikum Münster (DE) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007028599-A2 | A FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | Universitätsklinikum Münster (DE) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169483-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | EDNRB, EDNRA, ECE1 | ADRB2 108/4885HTR1A 334/4885BCHE 2453/4885 |
| US-20130004430-A1 | FLUORESCENT PHOTOPROBE FOR THE IMAGING OF ENDOTHELIN RECEPTORS | EDNRB, EDNRA, ECE1 | ADRB2 113/4885HTR1A 350/4885BCHE 2452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.