SCHEMBL4184734

SCHEMBL4184734

C=C(C)C(=O)OC(COc1ccc(-c2ccccc2)cc1)COc1cccc(OCC(COc2ccc(-c3ccccc3)cc2)OC(=O)C(=C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
LMNA P02545 2/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ACACB O00763 1/20 0.41
ACACA Q13085 1/20 0.41
MTNR1A P48039 3/20 0.41
MTNR1B P49286 3/20 0.41
FFAR4 Q5NUL3 2/20 0.41
HTR1D P28221 1/20 0.41
HTR1B P28222 1/20 0.41
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4198139 0.96 RXRA (0.49) MAPTRXRARXRBFFAR4FFAR1
SCHEMBL4188685 0.95 RXRA (0.47) MAPTRXRARXRBMTNR1AMTNR1B
SCHEMBL4184755 0.94 RXRA (0.48) RXRARXRBMTNR1AMTNR1BHTR1D
SCHEMBL11957216 0.94 MTNR1A (0.46) LMNAMAPK1L3MBTL1MTNR1AMTNR1B
SCHEMBL4197511 0.94 MAPT (0.50) MAPTLMNAMTNR1AMTNR1B
SCHEMBL4188595 0.94 MAPT (0.50) MAPTLMNAMTNR1AMTNR1B
SCHEMBL4197201 0.94 MAPT (0.47) MAPTLMNAMTNR1AMTNR1B
SCHEMBL4199988 0.90 ACACB (0.45) MAPTLMNAACACBACACAMTNR1A
SCHEMBL13383397 0.89 MAPT (0.46) MAPTLMNA
SCHEMBL4204184 0.89 MAPT (0.46) MAPTLMNAMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 MAPT 2073/4885RXRA 360/4885RXRB 538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.