SCHEMBL4199988

SCHEMBL4199988

C=C(C)C(=O)OC(COc1ccc(Oc2ccccc2)cc1)COc1ccc(-c2ccc(OCC(COc3ccc(Oc4ccccc4)cc3)OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACACB O00763 5/20 0.45
ACACA Q13085 4/20 0.45
LTA4H P09960 2/20 0.44
MAPT P10636 3/20 0.44
MTNR1A P48039 3/20 0.43
MTNR1B P49286 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
MMP12 P39900 1/20 0.40
MMP13 P45452 1/20 0.40
POLB P06746 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19944473 0.96 LTA4H (0.47) ACACBACACALTA4HMAPTMTNR1A
SCHEMBL4197201 0.96 MAPT (0.47) MAPTMTNR1AMTNR1BSMN1; SMN2POLB
SCHEMBL4197511 0.93 MAPT (0.50) MAPTMTNR1AMTNR1BSMN1; SMN2LMNA
SCHEMBL4188595 0.93 MAPT (0.50) MAPTMTNR1AMTNR1BSMN1; SMN2LMNA
SCHEMBL19944372 0.90 MTNR1A (0.50) MAPTMTNR1AMTNR1BPOLBLMNA
SCHEMBL4184734 0.90 MAPT (0.45) ACACBACACAMAPTMTNR1AMTNR1B
SCHEMBL4198745 0.90 FFAR4 (0.47) LTA4HMTNR1AMTNR1BSMN1; SMN2FFAR1
SCHEMBL4198139 0.89 RXRA (0.49) MAPTFFAR1FFAR4
SCHEMBL13383397 0.88 MAPT (0.46) MAPTSMN1; SMN2POLBLMNA
SCHEMBL4204184 0.88 MAPT (0.46) MAPTMTNR1AMTNR1BSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 ACACB 4227/4885ACACA 3147/4885LTA4H 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.