Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18769324 | 0.86 | GRIN2D (0.50) | MAOBALDH1A1TAAR1LOXL2CYP19A1 | |
| SCHEMBL43448 | 0.86 | ALDH1A1 (0.58) | MAOBALDH1A1TAAR1LOXL2CYP19A1 | |
| Hydrochloric Acid SCHEMBL2479666 | 0.84 | ALDH1A1 (0.55) | MAOBALDH1A1TAAR1LOXL2CYP19A1 | |
| SCHEMBL15502971 | 0.83 | TAAR1 (0.56) | TACR1MAOBTAAR1CYP19A1 | |
| SCHEMBL10175240 | 0.80 | TACR1 (0.45) | TACR1MAOBALDH1A1CYP19A1ACHE | |
| SCHEMBL15787170 | 0.79 | PTGS2 (0.47) | TACR1MAOBTAAR1CYP19A1 | |
| SCHEMBL3507655 | 0.78 | CYP19A1 (0.50) | MAOBALDH1A1TAAR1LOXL2CYP19A1 | |
| SCHEMBL10204849 | 0.78 | TACR1 (0.51) | TACR1MAOBALDH1A1CYP19A1ACHE | |
| SCHEMBL7621664 | 0.78 | TACR1 (0.44) | TACR1MAOBALDH1A1CYP19A1ACHE | |
| SCHEMBL12338023 | 0.78 | TACR1 (0.44) | TACR1MAOBALDH1A1TAAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303999-A1 | COMBINATORIAL PLATFORM FOR HIGH-THROUGHPUT POLYNUCLEOTIDE-ENCODED CATALYST DISCOVERY | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-09-28 | — | — | US | disclosed |
| US-9175038-B2 | Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2015-11-03 | — | — | US | disclosed |
| US-8927715-B2 | Inhibitors of 11β-hydroxysteroid dehydrogenase type 1 | VITAE PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8901316-B2 | Process for preparing aminoadamantyl carbamate derivatives | SHIONOGI & CO., LTD. (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20140142044-A1 | PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | The United States of America, as represented by the Secretary, Department of Health & Human Servic (US) | 2014-05-22 | — | — | US | disclosed |
| US-8524951-B2 | Process for production of hydroxyadamantaneamine | SHIONOGI & CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-20130197240-A1 | PROCESS FOR PREPARING AMINOADAMANTYL CARBAMATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2013-08-01 | — | — | US | disclosed |
| WO-2012170554-A1 | N-BIPHENYLMETHYLINDOLE MODULATORS OF PPARG | KAMENECKA THEODORE MARK (US) | 2012-12-13 | — | — | WO | disclosed |
| US-20120065146-A1 | PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2012-03-15 | — | — | US | disclosed |
| US-20110269971-A1 | PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE | SHIONOGI & CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| US-20110034455-A1 | INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | VITAE PHARMACEUTICALS, INC. | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034455-A1 | INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | HSD11B1, HSD17B1, HSD11B2 | TACR1 3280/4885MAOB 614/4885ALDH1A1 78/4885 |
| US-20130197240-A1 | PROCESS FOR PREPARING AMINOADAMANTYL CARBAMATE DERIVATIVES | HSD11B1, SRD5A1, ALDH7A1 | TACR1 998/4885MAOB 3203/4885ALDH1A1 520/4885 |
| US-20140142044-A1 | PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | PLK1, PLK4, PLK3 | TACR1 3864/4885MAOB 4213/4885ALDH1A1 4542/4885 |
| US-20120065146-A1 | PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | PLK1, PLK2, PLK4 | TACR1 4333/4885MAOB 4240/4885ALDH1A1 4782/4885 |
| US-20110269971-A1 | PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE | HAAO, CYP4A11, CYP4F11 | TACR1 1098/4885MAOB 320/4885ALDH1A1 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.