Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654293 | 1.00 | NOS1 (0.45) | NOS1TSHRALDH1A1CALM1CAMKK2 | |
| SCHEMBL28110854 | 0.83 | ACHE (0.60) | NOS1CALM1CAMKK2NOS2HTR7 | |
| SCHEMBL7582199 | 0.80 | MAPK1 (0.44) | TSHRALDH1A1 | |
| SCHEMBL4184944 | 0.80 | TSHR (0.38) | TSHRALDH1A1CALM1CAMKK2BCHE | |
| SCHEMBL1250219 | 0.78 | ENPP2 (0.52) | TSHRF10 | |
| SCHEMBL27213436 | 0.78 | HRH3 (0.50) | NOS1TSHRALDH1A1NOS2 | |
| SCHEMBL850832 | 0.78 | CALM1 (0.64) | TSHRALDH1A1CALM1CAMKK2HTR7 | |
| SCHEMBL29547354 | 0.78 | CALM1 (0.64) | TSHRALDH1A1CALM1CAMKK2HTR7 | |
| SCHEMBL29172589 | 0.77 | ALOX5 (0.45) | ACHE | |
| SCHEMBL29643534 | 0.77 | ENPP2 (0.48) | NOS1ALDH1A1NOS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467615-A | Azolopyrimidines include its pharmaceutical composition and its preparation method and application | SICHUAN KELUN BOTAI BIOMEDICAL CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-106167464-A | One class quinoline derivatives, Preparation Method And The Use | 中国医学科学院药物研究所 | 2016-11-30 | — | — | CN | disclosed |