Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841388 | 0.83 | TSHR (0.60) | LMNACYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL8245365 | 0.81 | KMT2A (0.65) | LMNAHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL13547569 | 0.80 | TRPC5 (0.49) | LMNACYP3A4CYP2D6ALDH1A1KDM4E | |
| SCHEMBL3222264 | 0.80 | CD274 (0.55) | LMNAHSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL5549334 | 0.79 | MEN1 (0.68) | LMNACYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL13034201 | 0.79 | SIGMAR1 (0.58) | LMNAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL24324971 | 0.78 | SIGMAR1 (0.47) | LMNACYP3A4CYP2D6KDM4EHIF1A | |
| SCHEMBL20715468 | 0.77 | ALDH1A1 (0.48) | LMNAALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL2184152 | 0.76 | KMT2A (0.50) | LMNAHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL6671580 | 0.76 | CYP3A4 (0.56) | LMNACYP3A4CYP2C19CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | HCAR1, ADGRE5, ALK | LMNA 1673/4885CYP3A4 1449/4885CYP2C19 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.