SCHEMBL24324971

SCHEMBL24324971

CCCc1ccc(NCCN2CCOCC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
POLB P06746 2/20 0.45
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
LMNA P02545 2/20 0.45
KDM4E B2RXH2 1/20 0.45
HIF1A Q16665 1/20 0.45
EPAS1 Q99814 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
ABL1 P00519 1/20 0.44
BCR P11274 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13547569 0.88 TRPC5 (0.49) SIGMAR1KMT2AMEN1POLBLMNA
SCHEMBL26964867 0.85 KMT2A (0.46) SIGMAR1KMT2AMEN1POLBLMNA
SCHEMBL13283790 0.85 SIGMAR1 (0.53) SIGMAR1KMT2AMEN1POLBTHRA
SCHEMBL13841388 0.81 TSHR (0.60) KMT2AMEN1POLBLMNAKDM4E
SCHEMBL20715468 0.81 ALDH1A1 (0.48) SIGMAR1KMT2AMEN1POLBLMNA
SCHEMBL8245365 0.80 KMT2A (0.65) SIGMAR1KMT2AMEN1THRBLMNA
SCHEMBL3222264 0.78 CD274 (0.55) KMT2AMEN1LMNAKDM4EABL1
SCHEMBL5549334 0.78 MEN1 (0.68) SIGMAR1KMT2AMEN1POLBLMNA
SCHEMBL4185225 0.78 LMNA (0.59) KMT2AMEN1LMNAKDM4EHIF1A
SCHEMBL13034201 0.78 SIGMAR1 (0.58) SIGMAR1KMT2AMEN1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2022-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME GPR119, SSTR5, SSTR2 SIGMAR1 837/4885KMT2A 3970/4885MEN1 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.