Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.54 |
| ▸ | DRD1 | P21728 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | DRD5 | P21918 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184854 | 0.96 | LTA4H (0.58) | USP2ALDH1A1HPGDHTR1ADRD2 | |
| SCHEMBL4179288 | 0.89 | USP2 (0.48) | USP2ALDH1A1HPGDHTR1ADRD2 | |
| SCHEMBL4178438 | 0.88 | USP2 (0.53) | USP2ALDH1A1HPGDHTR1ADRD2 | |
| SCHEMBL4182952 | 0.88 | KDM4E (0.54) | USP2ALDH1A1HPGDHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL11815787 | 0.87 | TSHR (0.61) | ALDH1A1HTR1ADRD2DRD3HTR2A | |
| SCHEMBL13698800 | 0.86 | USP2 (0.73) | USP2ALDH1A1HPGDHTR1ADRD2 | |
| SCHEMBL1730776 | 0.85 | USP2 (0.54) | USP2ALDH1A1HPGDHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL1730768 | 0.84 | USP2 (0.71) | USP2ALDH1A1HPGDHTR1ADRD2 | |
| SCHEMBL4168448 | 0.84 | HRH3 (0.47) | USP2ALDH1A1HPGDHTR1ADRD2 | |
| SCHEMBL4179707 | 0.84 | DRD2 (0.53) | USP2ALDH1A1HPGDHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221607-A1 | Piperazine Derivatives | M'S SCIENCE CORPORATION (JP) | 2009-09-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221607-A1 | Piperazine Derivatives | SIGMAR1, OPRL1, OPRK1 | USP2 3002/4885ALDH1A1 305/4885HPGD 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.