Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182651 | 0.86 | NPC1 (0.31) | — | |
| SCHEMBL4168497 | 0.84 | DCTPP1 (0.35) | NFE2L2 | |
| SCHEMBL4178066 | 0.81 | AHR (0.40) | — | |
| SCHEMBL4172375 | 0.80 | NFE2L2 (0.34) | NFE2L2 | |
| SCHEMBL4174113 | 0.80 | NFE2L2 (0.36) | NFE2L2 | |
| SCHEMBL4168514 | 0.79 | TRPA1 (0.30) | — | |
| SCHEMBL4177697 | 0.76 | PDE4B (0.30) | — | |
| SCHEMBL4168484 | 0.75 | CHRNB2 (0.39) | — | |
| SCHEMBL4174412 | 0.75 | GRM4 (0.35) | NFE2L2 | |
| SCHEMBL4175680 | 0.74 | CHRNA7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179921-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-20130197029-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338443-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197029-A1 | CHEMICAL COMPOUNDS | MRM1, H1-0, RO60 | NFE2L2 1211/4885 |
| US-20140179921-A1 | CHEMICAL COMPOUNDS | H1-0, REL, ZYX | NFE2L2 169/4885 |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | MRM1, MNS1, CHRM1 | NFE2L2 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.