SCHEMBL4185814

SCHEMBL4185814

CCCCO[Si](C)(C)O[SiH](C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26676536 0.93 DNM1 (0.32)
SCHEMBL26676600 0.86
SCHEMBL151806 0.80 ADRB2 (0.43) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL29134232 0.79
SCHEMBL26676546 0.79
SCHEMBL5711968 0.79 ADRB2 (0.35) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL5711943 0.79 ADRB2 (0.35) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL15577263 0.77 ADRB2 (0.33) ADRB2ADRB1ADRB3CYP3A4TSHR
SCHEMBL16522928 0.77
SCHEMBL2950261 0.75 TSHR (0.40) ADRB2ADRB1ADRB3CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230386825-A1 ALKOXYDISILOXANES AND DENSE ORGANOSILICA FILMS MADE THEREFROM VERSUM MATERIALS US, LLC 2023-11-30 US claimed
EP-4211291-A1 ALKOXYDISILOXANES AND DENSE ORGANOSILICA FILMS MADE THEREFROM Versum Materials US, LLC (US) 2023-07-19 EP claimed
WO-2022087151-A1 ALKOXYDISILOXANES AND DENSE ORGANOSILICA FILMS MADE THEREFROM VERSUM MATERIALS US, LLC (US) 2022-04-28 WO claimed
US-11642304-B2 Dimethylsiloxane-alkylene oxide copolymers CORNELIUS GROUP PLC (GB) 2023-05-09 US disclosed
US-20090247649-A1 Compositions using evaporable silicone carriers for cosmetics, cleaning and care product compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2009-10-01 US disclosed
US-20070224295-A1 COMPOSITIONS USING EVAPORABLE SILICONE CARRIERS FOR COSMETICS, CLEANING AND CARE PRODUCT COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS (FORMERLY GE ADVANCED MATERIALS) (US) 2007-09-27 US disclosed
US-20050265942-A1 Compositions using evaporable silicone carriers for cosmetics, cleaning and care product compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2005-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11642304-B2 Dimethylsiloxane-alkylene oxide copolymers ZYX, YWHAZ, PRXL2A ADRB2 1709/4885ADRB1 2689/4885ADRB3 2857/4885
US-20070224295-A1 COMPOSITIONS USING EVAPORABLE SILICONE CARRIERS FOR COSMETICS, CLEANING AND CARE PRODUCT COMPOSITIONS SCO2, B2M, SMURF1 ADRB2 2599/4885ADRB1 3209/4885ADRB3 2207/4885
US-20230386825-A1 ALKOXYDISILOXANES AND DENSE ORGANOSILICA FILMS MADE THEREFROM WASF2, ORMDL3, WEE2 ADRB2 2821/4885ADRB1 3853/4885ADRB3 3758/4885
US-20090247649-A1 Compositions using evaporable silicone carriers for cosmetics, cleaning and care product compositions SCO2, B2M, SMURF1 ADRB2 2595/4885ADRB1 3203/4885ADRB3 2212/4885
US-20050265942-A1 Compositions using evaporable silicone carriers for cosmetics, cleaning and care product compositions SCO2, B2M, SMURF1 ADRB2 2599/4885ADRB1 3209/4885ADRB3 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.