SCHEMBL418657

SCHEMBL418657

Cc1cc(C)c(B(c2ccc(-c3ccc(B(c4c(C)cc(C)cc4C)c4c(C)cc(C)cc4C)s3)s2)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 4/20 0.33
ESR2 Q92731 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1309487 0.98 ESR2 (0.36) RAPGEF4ESR2HSD17B1HSD17B2
SCHEMBL1309857 0.91 HSD17B1 (0.41) RAPGEF4ESR2HSD17B1HSD17B2
SCHEMBL127327 0.90 RAPGEF4 (0.37) RAPGEF4
SCHEMBL18807405 0.87 RAPGEF4 (0.31) RAPGEF4ESR2HSD17B1HSD17B2
SCHEMBL17880693 0.87 HSD17B1 (0.30) ESR2HSD17B1HSD17B2
SCHEMBL17449601 0.87 FFAR4 (0.34) ESR2HSD17B1HSD17B2
SCHEMBL17146818 0.84 RAPGEF4 (0.33) RAPGEF4
SCHEMBL16722869 0.82 RAPGEF4 (0.38) RAPGEF4
SCHEMBL14592727 0.81 HSD17B1 (0.35) HSD17B1HSD17B2
SCHEMBL14592725 0.80 HSD17B1 (0.39) ESR2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221649-A1 BORON CONTAINING HOLE BLOCKING LAYER PHOTOCONDUCTOR XEROX CORPORATION (US) 2010-09-02 US claimed
US-7670738-B2 Boron containing photoconductors XEROX CORPORATION (US) 2010-03-02 US claimed
US-20090061338-A1 BORON CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US claimed
US-20050170211-A1 Organic electroluminescent element SHARP KABUSHIKI KAISHA 2005-08-04 US claimed
WO-2003086025-A1 RGB PATTERNING OF ORGANIC LIGHT-EMITTING DEVICES USING PHOTO-BLEACHABLE EMITTERS DISPERSED IN A COMMON HOST THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2003-10-16 WO claimed
US-20030186078-A1 RGB patterning of organic light-emitting devices using photo-bleachable emitters dispersed in a common host NAVY, THE UNTIED STATES OF AMERICAAS REPRESENTED BY THE SECRETARY OF THE 2003-10-02 US claimed
US-20020067124-A1 Universal host for RG or RGB emission in organic light emitting devices KAFAFI ZAKYA H (US) 2002-06-06 US claimed
US-20200043987-A1 DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2020-02-06 US disclosed
US-8525159-B2 Organic light emitting element SHARP KABUSHIKI KAISHA (JP) 2013-09-03 US disclosed
US-8497500-B2 Organic EL device SHARP KABUSHIKI KAISHA (JP) 2013-07-30 US disclosed
US-8492752-B2 2013-07-23 US disclosed
US-20120280214-A1 ORGANIC EL ELEMENT HAVING CATHODE BUFFER LAYER FUJI ELECTRIC HOLDINGS CO., LTD. 2012-11-08 US disclosed
US-8299458-B2 Organic electroluminescent device SHARP KABUSHIKI KAISHA (JP) 2012-10-30 US disclosed
WO-2003086025-A1 RGB PATTERNING OF ORGANIC LIGHT-EMITTING DEVICES USING PHOTO-BLEACHABLE EMITTERS DISPERSED IN A COMMON HOST THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2003-10-16 WO disclosed
US-H2084-H1 6,13-diphenylpentacene having narrow spectral emmitance, used in electrical and electronic apparatus; electroluminescence THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2003-10-07 US disclosed
US-20030186078-A1 RGB patterning of organic light-emitting devices using photo-bleachable emitters dispersed in a common host NAVY, THE UNTIED STATES OF AMERICAAS REPRESENTED BY THE SECRETARY OF THE 2003-10-02 US disclosed
US-20030164678-A1 Vinyl polymer and organic electroluminescent device DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-04 US disclosed
US-20020067124-A1 Universal host for RG or RGB emission in organic light emitting devices KAFAFI ZAKYA H (US) 2002-06-06 US disclosed
WO-2001045469-A1 PENTACENE DERIVATIVES AS RED EMITTERS IN ORGANIC LIGHT EMITTING DEVICES THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2001-06-21 WO disclosed
JP-2001072971-A ELECTROLUMINESCENT ELEMENT UNIV OSAKA 2001-03-21 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030164678-A1 Vinyl polymer and organic electroluminescent device HVCN1, VMP1, ELAVL1 RAPGEF4 2203/4885ESR2 536/4885HSD17B1 2027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.