SCHEMBL1309487

SCHEMBL1309487

Cc1cc(C)c(B(c2ccc(-c3ccc(-c4ccc(B(c5c(C)cc(C)cc5C)c5c(C)cc(C)cc5C)s4)s3)s2)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
RAPGEF4 Q8WZA2 2/20 0.32
ESR1 P03372 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418657 0.98 RAPGEF4 (0.33) ESR2HSD17B1HSD17B2RAPGEF4
SCHEMBL1309857 0.89 HSD17B1 (0.41) ESR2HSD17B1HSD17B2RAPGEF4
SCHEMBL18807405 0.89 RAPGEF4 (0.31) ESR2HSD17B1HSD17B2RAPGEF4
SCHEMBL17880693 0.89 HSD17B1 (0.30) ESR2HSD17B1HSD17B2
SCHEMBL17449601 0.89 FFAR4 (0.34) ESR2HSD17B1HSD17B2
SCHEMBL127327 0.88 RAPGEF4 (0.37) RAPGEF4
SCHEMBL17146818 0.82 RAPGEF4 (0.33) RAPGEF4
SCHEMBL16722869 0.81 RAPGEF4 (0.38) RAPGEF4
SCHEMBL18030898 0.81
SCHEMBL12360761 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221649-A1 BORON CONTAINING HOLE BLOCKING LAYER PHOTOCONDUCTOR XEROX CORPORATION (US) 2010-09-02 US claimed
US-7670738-B2 Boron containing photoconductors XEROX CORPORATION (US) 2010-03-02 US claimed
US-20090061338-A1 BORON CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US claimed
US-12048175-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-07-23 US disclosed
US-12048175-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-07-23 US disclosed
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2024-01-25 US disclosed
US-11832516-B2 Light-emitting material, compound, long-persistent phosphor and light-emitting element KYULUX, INC. (JP) 2023-11-28 US disclosed
US-11832516-B2 Light-emitting material, compound, long-persistent phosphor and light-emitting element KYULUX, INC. (JP) 2023-11-28 US disclosed
EP-3843168-B1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE UNIV KYUSHU NAT UNIV CORP (JP) 2023-10-11 EP disclosed
US-11778904-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-10-03 US disclosed
US-11778904-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-10-03 US disclosed
US-7160634-B2 Vinyl polymer and organic electroluminescent device Shirota, Yasuhiko (JP) 2007-01-09 US disclosed
US-7160634-B2 Vinyl polymer and organic electroluminescent device Shirota, Yasuhiko (JP) 2007-01-09 US disclosed
US-7160634-B2 Vinyl polymer and organic electroluminescent device Shirota, Yasuhiko (JP) 2007-01-09 US disclosed
US-7038086-B2 Vinyl polymer and organic electroluminescent device Shirota, Yasuhiko (JP) 2006-05-02 US disclosed
US-20060049750-A1 Vinyl polymer and organic electroluminescent device SHIROTA YASUHIKO 2006-03-09 US disclosed
US-20060036114-A1 Organoboron luminescent compounds and methods of making and using same QUEEN'S UNIVERSITY AT KINGSTON (CA) 2006-02-16 US disclosed
US-20040199016-A1 Vinyl polymer and organic electroluminescent device DAICEL CHEMICAL INDUSTRIES, LTD. 2004-10-07 US disclosed
US-6784318-B2 HEAT RESISTANCE YASUHIKO SHIROTA (JP) 2004-08-31 US disclosed
US-20030164678-A1 Vinyl polymer and organic electroluminescent device DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT NR2E3, CRY1, ESR1 ESR2 7/4885HSD17B1 4314/4885HSD17B2 3903/4885
US-11778904-B2 Composition of matter for use in organic light-emitting diodes CRY2, SLCO1B3, NDUFV3 ESR2 362/4885HSD17B1 2535/4885HSD17B2 2064/4885
US-11832516-B2 Light-emitting material, compound, long-persistent phosphor and light-emitting element NR2E3, CRY1, ESR1 ESR2 7/4885HSD17B1 4314/4885HSD17B2 3903/4885
US-20060036114-A1 Organoboron luminescent compounds and methods of making and using same SLC43A1, SLC1A5, SLC9B2 ESR2 1583/4885HSD17B1 2055/4885HSD17B2 2238/4885
US-20060049750-A1 Vinyl polymer and organic electroluminescent device HVCN1, VCL, ELAVL1 ESR2 266/4885HSD17B1 1697/4885HSD17B2 1533/4885
US-20030164678-A1 Vinyl polymer and organic electroluminescent device HVCN1, VMP1, ELAVL1 ESR2 536/4885HSD17B1 2027/4885HSD17B2 2065/4885
US-20040199016-A1 Vinyl polymer and organic electroluminescent device HVCN1, VMP1, ELAVL1 ESR2 446/4885HSD17B1 1995/4885HSD17B2 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.