SCHEMBL127327

SCHEMBL127327

Cc1cc(C)c(B(c2ccc(B(c3c(C)cc(C)cc3C)c3c(C)cc(C)cc3C)s2)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 8/20 0.37
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
TP53 P04637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16722869 0.92 RAPGEF4 (0.38) RAPGEF4CYP1A2CYP2A6FFAR4
SCHEMBL418657 0.90 RAPGEF4 (0.33) RAPGEF4
SCHEMBL17146818 0.90 RAPGEF4 (0.33) RAPGEF4
SCHEMBL16407584 0.89 RAPGEF4 (0.30) RAPGEF4
SCHEMBL1309487 0.88 ESR2 (0.36) RAPGEF4
SCHEMBL15032372 0.87 RAPGEF4 (0.34) RAPGEF4TP53TDP1
SCHEMBL1309857 0.85 HSD17B1 (0.41) RAPGEF4CYP1A2CYP2A6
SCHEMBL19287923 0.83 CYP1A2 (0.32) RAPGEF4CYP1A2CYP2A6FFAR4
SCHEMBL24180805 0.80
SCHEMBL17880693 0.78 HSD17B1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221649-A1 BORON CONTAINING HOLE BLOCKING LAYER PHOTOCONDUCTOR XEROX CORPORATION (US) 2010-09-02 US claimed
US-7670738-B2 Boron containing photoconductors XEROX CORPORATION (US) 2010-03-02 US claimed
US-20090061338-A1 BORON CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US claimed
EP-4329431-A2 NOVEL HETEROLEPTIC IRIDIUM COMPLEXES Universal Display Corporation (US) 2024-02-28 EP disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
EP-3981776-B1 USE OF AN ANCILLARY LIGAND IN A PHOSPHORESCENT METAL COMPLEX COMPOUND UNIVERSAL DISPLAY CORP (US) 2023-11-15 EP disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed
US-20090061337-A1 PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061337-A1 PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061338-A1 BORON CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061338-A1 BORON CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061336-A1 LIGHT STABILIZER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061336-A1 LIGHT STABILIZER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20080203406-A1 Layer Assembly for a Light-Emitting Component NOVALDE GMBH (DE) 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR RAPGEF4 3807/4885CYP1A2 1165/4885CYP2A6 1599/4885
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES OXA1L, PAICS, ORC3 RAPGEF4 4264/4885CYP1A2 1432/4885CYP2A6 3438/4885
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES PAICS, CYBA, OXA1L RAPGEF4 3617/4885CYP1A2 1262/4885CYP2A6 3735/4885
US-11917902-B2 Organic electroluminescent materials and devices SOD1, NDUFV1, L1CAM RAPGEF4 3103/4885CYP1A2 1132/4885CYP2A6 3058/4885
US-11832507-B2 Organic electroluminescent materials and devices MLX, LBR, LDLR RAPGEF4 3807/4885CYP1A2 1165/4885CYP2A6 1599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.