Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189252 | 0.86 | ALOX15 (0.58) | ALOX15NPC1ALDH1A1PKMTSHR | |
| SCHEMBL4182877 | 0.83 | PTGS1 (0.55) | ALOX15NPC1RAB9A | |
| SCHEMBL4256095 | 0.80 | MEN1 (0.64) | ALOX15NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4178453 | 0.79 | GAA (0.56) | NPC1ALDH1A1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL4185825 | 0.77 | GRM5 (0.53) | GRM5CYP3A4FFAR2CYP1A2CYP2C9 | |
| SCHEMBL4252112 | 0.76 | ALOX15 (0.78) | CYP3A4ALOX15CYP1A2CYP2C9 | |
| SCHEMBL4250340 | 0.76 | ALOX15 (0.61) | ALOX15NPC1ALDH1A1PKMRAB9A | |
| SCHEMBL30761102 | 0.76 | GRM5 (0.53) | GRM5CYP3A4FFAR2NPC1ALDH1A1 | |
| SCHEMBL30761214 | 0.74 | NPC1 (0.59) | GRM5NPC1ALDH1A1PKMRAB9A | |
| SCHEMBL4256925 | 0.73 | NPC1 (0.51) | ALOX15NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143440-A1 | Pyrazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143440-A1 | Pyrazoles Useful in the Treatment of Inflammation | ALOX15, ALOX12, ALOX15B | GRM5 1410/4885CYP3A4 89/4885FFAR2 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.