Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187822 | 0.86 | GRM5 (0.51) | ALOX15BRD4RAB9ASMN1; SMN2TSHR | |
| SCHEMBL4182877 | 0.82 | PTGS1 (0.55) | ALOX15RAB9ANPC1 | |
| SCHEMBL4256925 | 0.81 | NPC1 (0.51) | ALOX15RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4178453 | 0.81 | GAA (0.56) | L3MBTL1RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4192471 | 0.78 | L3MBTL1 (0.58) | ALOX15L3MBTL1BRD4PTK2RAB9A | |
| SCHEMBL4253110 | 0.75 | ALOX15 (0.68) | ALOX15RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL4675605 | 0.74 | RAB9A (0.63) | ALOX15L3MBTL1BRD4PTK2RAB9A | |
| SCHEMBL24654650 | 0.73 | L3MBTL1 (0.78) | ALOX15L3MBTL1BRD4PTK2RAB9A | |
| SCHEMBL29837506 | 0.73 | L3MBTL1 (0.66) | ALOX15L3MBTL1BRD4PTK2RAB9A | |
| SCHEMBL28764679 | 0.73 | L3MBTL1 (0.66) | ALOX15L3MBTL1BRD4PTK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143440-A1 | Pyrazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143440-A1 | Pyrazoles Useful in the Treatment of Inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885L3MBTL1 2716/4885BRD4 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.