Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | RGS12 | O14924 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HEXA | P06865 | 3/20 | 0.45 |
| ▸ | HEXB | P07686 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4997819 | 0.91 | HEXA (0.55) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL4448748 | 0.85 | DNMT1 (0.41) | RAB9ASMN1; SMN2HEXAHEXBDNMT1 | |
| SCHEMBL11877346 | 0.84 | DNMT1 (0.46) | ALDH1A1MEN1KMT2AHTTRGS12 | |
| SCHEMBL11500864 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AHTTRGS12 | |
| SCHEMBL10396735 | 0.82 | BCHE (0.44) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2641523 | 0.82 | POLB (0.60) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL4997234 | 0.81 | MEN1 (0.49) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5953603 | 0.80 | SIRT1 (0.59) | HEXAHEXB | |
| SCHEMBL6586389 | 0.80 | DNMT1 (0.43) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL12235635 | 0.78 | CYP1B1 (0.53) | KDM4EALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029545-B1 | Bisnaphthalimidopropyl derivatives with anti-parasite and anti-cancer activity | UNIV DO PORTO (PT) | 2014-12-17 | — | — | EP | disclosed |
| US-8350036-B2 | Bisnaphthalimidopropyl derivative compounds with anti-parasite and anti-cancer activity | UNIVERSIDADE DO PORTO (PT) | 2013-01-08 | — | — | US | disclosed |
| US-20090062329-A1 | BISNAPHTHALIMIDOPROPYL DERIVATIVE COMPOUNDS WITH ANTI-PARASITE AND ANTI-CANCER ACTIVITY | UNIVERSIDADE DO PORTO (PT) | 2009-03-05 | — | — | US | disclosed |
| EP-2029545-A2 | BISNAPHTHALIMIDOPROPYL DERIVATIVE COMPOUNDS WITH ANTI-PARASITE AND ANTI-CANCER ACTIVITY | Universidade Do Porto (PT) | 2009-03-04 | — | — | EP | disclosed |
| WO-2008007262-A2 | BISNAPHTHALIMIDOPROPYL DERIVATIVE COMPOUNDS WITH ANTI-PARASITE AND ANTI-CANCER ACTIVITY | UNIVERSIDADE DO PORTO (PT) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062329-A1 | BISNAPHTHALIMIDOPROPYL DERIVATIVE COMPOUNDS WITH ANTI-PARASITE AND ANTI-CANCER ACTIVITY | DCPS, SI, MYADM | KDM4E 2357/4885ALDH1A1 3939/4885MEN1 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.