SCHEMBL4188364

SCHEMBL4188364

C[C@@H](CC1CCCCC1)NCc1cccnc1NS(=O)(=O)c1ccc(-c2ccno2)s1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.35
PRF1 P14222 1/20 0.34
MAPT P10636 7/20 0.33
PKM P14618 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
F2RL1 P55085 3/20 0.32
TP53 P04637 3/20 0.31
F2 P00734 1/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4190604 0.88 NPC1 (0.39) POLBPRF1MAPTPKMRXFP1
SCHEMBL4197648 0.85 KMT2A (0.40) POLBMAPTPKMRXFP1F2
Hydrochloric Acid SCHEMBL4197873 0.84 PRF1 (0.37) POLBPRF1MAPTTP53NPC1
SCHEMBL4197365 0.80 ALDH1A1 (0.41) TP53NPC1LMNA
SCHEMBL4194794 0.80 ALDH1A1 (0.41) TP53NPC1LMNA
SCHEMBL4184314 0.78 EDNRA (0.38) PKMLMNA
Cyclopentane SCHEMBL4190609 0.77 NPC1 (0.48) POLBPRF1MAPTPKMRXFP1
SCHEMBL4197533 0.75 PKM (0.36) POLBMAPTPKMRXFP1TP53
SCHEMBL14344109 0.74 GHSR (0.42) MAPTPKMRXFP1F2LMNA
SCHEMBL4193400 0.74 KDM4E (0.37) POLBPRF1MAPTPKMRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 POLB 215/4885PRF1 1166/4885MAPT 2269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.