SCHEMBL4188725

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4187170	0.96	CYP1A2 (0.38)	CYP1A2CYP3A4CYP2D6CYP2C19KDM4E
	SCHEMBL4472512	0.94	TSPO (0.36)	CYP1A2CYP3A4CYP2D6CYP2C19KDM4E
	SCHEMBL4191228	0.90	PTGS2 (0.39)	KDM4EALDH1A1NPC1RAB9AHPGD
	SCHEMBL4479968	0.90	TSPO (0.39)	KDM4EALDH1A1NPC1RAB9APTGS2
	SCHEMBL4191664	0.88	ICAM1 (0.39)	KDM4EALDH1A1NPC1RAB9AHPGD
	SCHEMBL4188865	0.87	CYP1A2 (0.39)	CYP1A2CYP3A4CYP2D6CYP2C19KDM4E
	SCHEMBL4467050	0.84	CYP1A2 (0.42)	CYP1A2CYP3A4CYP2D6CYP2C19KDM4E
	SCHEMBL4198387	0.84	CYP1A2 (0.45)	CYP1A2CYP3A4CYP2D6CYP2C19KDM4E
	SCHEMBL4478135	0.83	ICAM1 (0.41)	KDM4EALDH1A1NPC1RAB9ALMNA
	SCHEMBL4193967	0.83	MLYCD (0.38)	KDM4EALDH1A1PTGS2ICAM1SELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.