Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178000 | 0.94 | CYP19A1 (0.42) | MEN1NSD2KMT2AAPAF1CYP1A2 | |
| SCHEMBL4194353 | 0.83 | CYP19A1 (0.32) | MEN1NSD2KMT2ACYP1A2CYP2D6 | |
| SCHEMBL4198995 | 0.82 | MEN1 (0.37) | MEN1NSD2KMT2AAPAF1CYP1A2 | |
| SCHEMBL4199075 | 0.79 | DRD2 (0.38) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4190666 | 0.78 | KMT2A (0.32) | MEN1NSD2KMT2AAPAF1CYP19A1 | |
| SCHEMBL4197474 | 0.78 | KDM4E (0.35) | MEN1NSD2KMT2ACYP19A1POLB | |
| SCHEMBL11184971 | 0.78 | CYP19A1 (0.43) | MEN1NSD2KMT2ACYP1A2CYP2D6 | |
| SCHEMBL4186617 | 0.78 | ALDH1A1 (0.32) | MEN1NSD2KMT2ACYP1A2CYP2D6 | |
| SCHEMBL4200315 | 0.78 | KDM4E (0.42) | MEN1NSD2KMT2ACYP1A2CYP2D6 | |
| SCHEMBL4191708 | 0.77 | KMT2A (0.34) | MEN1NSD2KMT2APIK3CAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | CASP4, CASP8, CASP1 | MEN1 2002/4885NSD2 4029/4885KMT2A 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.