Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196907 | 0.84 | ALDH1A1 (0.57) | MEN1LMNAKMT2A | |
| SCHEMBL4188256 | 0.78 | KDM4E (0.47) | LMNAKMT2AL3MBTL1 | |
| SCHEMBL4185865 | 0.76 | KMT2A (0.48) | MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL4194030 | 0.76 | LMNA (0.55) | MEN1LMNAKMT2A | |
| SCHEMBL4190437 | 0.75 | LMNA (0.61) | MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL4176815 | 0.72 | HPGD (0.51) | MEN1LMNAKMT2A | |
| SCHEMBL4185817 | 0.71 | ALDH1A1 (0.51) | MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL4732905 | 0.70 | L3MBTL1 (0.81) | MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL4734500 | 0.69 | L3MBTL1 (0.50) | L3MBTL1 | |
| SCHEMBL31278207 | 0.69 | KDM4E (0.48) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | claimed |