Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196907 | 0.90 | ALDH1A1 (0.57) | LMNAALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL13890885 | 0.90 | LMNA (0.55) | LMNAALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL4190437 | 0.81 | LMNA (0.61) | LMNAALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL4346565 | 0.78 | ALDH1A1 (0.67) | LMNAALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL4176815 | 0.78 | HPGD (0.51) | LMNAALDH1A1SMN1; SMN2MEN1HPGD | |
| SCHEMBL4187652 | 0.77 | ALDH1A1 (0.49) | LMNAALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL4734529 | 0.77 | KDM4E (0.64) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4187378 | 0.76 | KDM4E (0.51) | LMNAALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL4189591 | 0.76 | MEN1 (0.43) | LMNAMEN1KMT2A | |
| SCHEMBL4185865 | 0.75 | KMT2A (0.48) | LMNAALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | claimed |
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | disclosed |