SCHEMBL4189896

SCHEMBL4189896

CC(CC1CCCCC1)NCc1ccccc1NS(=O)(=O)c1cccc2sc(N)nc12

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 1/20 0.37
PKM P14618 1/20 0.37
PKLR P30613 2/20 0.36
SLC40A1 Q9NP59 3/20 0.33
NFKBIA P25963 2/20 0.33
RELA Q04206 2/20 0.33
PI4KB Q9UBF8 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.32
USP30 Q70CQ3 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4204377 0.83 KDM4E (0.43) MEN1KMT2AKDM4EPKMSLC40A1
SCHEMBL4192953 0.82 MAPT (0.47) MEN1KMT2AKDM4EPKMALDH1A1
SCHEMBL4186018 0.82 ALDH1A1 (0.43) KMT2AKDM4EPKMALDH1A1LMNA
SCHEMBL4197348 0.82 KDM4E (0.40) MEN1KMT2AKDM4EPKMPI4KB
SCHEMBL4197657 0.81 ALDH1A1 (0.44) KMT2AKDM4EPKMALDH1A1LMNA
SCHEMBL4188022 0.81 KDM4E (0.39) MEN1KMT2AKDM4EPKMALDH1A1
SCHEMBL4189882 0.81 MEN1 (0.62) MEN1KMT2AKDM4EALDH1A1TDP1
SCHEMBL4201910 0.80 CNR1 (0.41) MEN1KMT2AKDM4EPKMRELA
SCHEMBL4204383 0.80 KDM4E (0.40) MEN1KMT2AKDM4EPKMALDH1A1
SCHEMBL4200095 0.79 CCR2 (0.41) KDM4EPKMALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
CN-101203504-B Antimicrobial agents RANBAXY LAB LTD 2012-11-14 CN claimed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
CN-101203504-A Antimicrobial agents RANBAXY LAB LTD (IN) 2008-06-18 CN claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
CN-101203504-B Antimicrobial agents RANBAXY LAB LTD 2012-11-14 CN disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
CN-101203504-A Antimicrobial agents RANBAXY LAB LTD (IN) 2008-06-18 CN disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 MEN1 3776/4885KMT2A 2047/4885KDM4E 3328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.