Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367063 | 0.82 | APP (0.52) | APPAKR1C2AKR1C1VCPHNF4A | |
| SCHEMBL5684797 | 0.78 | AKR1C2 (0.49) | APPAKR1C2AKR1C1VCPHNF4A | |
| SCHEMBL5685392 | 0.78 | GRM5 (0.56) | APPAKR1C2AKR1C1HNF4AFFAR1 | |
| SCHEMBL4848452 | 0.78 | CES2 (0.56) | APPAKR1C2AKR1C1HNF4AFFAR1 | |
| SCHEMBL2707734 | 0.78 | APP (0.52) | APPAKR1C2AKR1C1VCPHNF4A | |
| SCHEMBL16103102 | 0.76 | RARB (0.56) | APPAKR1C2AKR1C1HNF4AFFAR1 | |
| SCHEMBL2746660 | 0.76 | AKR1C2 (0.50) | APPAKR1C2AKR1C1VCPHNF4A | |
| Hydrochloric Acid SCHEMBL2746715 | 0.76 | AKR1C2 (0.50) | APPAKR1C2AKR1C1VCPHNF4A | |
| Hydrochloric Acid SCHEMBL2709682 | 0.76 | AKR1C2 (0.50) | APPAKR1C2AKR1C1VCPHNF4A | |
| SCHEMBL2450399 | 0.76 | APP (0.80) | APPAKR1C2AKR1C1HNF4AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |
| US-20040053033-A1 | Multifunctional monomers and their use in making cross-linked polymers and porous films | NIU Q JASON (US) | 2004-03-18 | — | — | US | disclosed |