Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15611234 | 0.83 | GRM5 (0.64) | GRM5NPC1RAB9AMAPTPOLB | |
| SCHEMBL4367063 | 0.83 | APP (0.52) | NPC1RAB9AMAPTTSHRAPP | |
| SCHEMBL1479638 | 0.80 | GRM5 (0.56) | GRM5NPC1RAB9AMAPTPOLB | |
| SCHEMBL4848452 | 0.80 | CES2 (0.56) | NPC1RAB9AMAPTAPPAKR1C2 | |
| SCHEMBL5684797 | 0.80 | AKR1C2 (0.49) | GRM5NPC1RAB9AMAPTAPP | |
| SCHEMBL2707734 | 0.79 | APP (0.52) | NPC1RAB9ATSHRAPPDHODH | |
| Hydrochloric Acid SCHEMBL1476861 | 0.79 | GRM5 (0.55) | GRM5NPC1RAB9AMAPTPOLB | |
| SCHEMBL4189999 | 0.78 | APP (0.46) | GRM5NPC1RAB9AMAPTAPP | |
| SCHEMBL16103102 | 0.78 | RARB (0.56) | GRM5MAPTCYP3A4TSHRAPP | |
| Hydrochloric Acid SCHEMBL2709682 | 0.78 | AKR1C2 (0.50) | NPC1RAB9ATSHRAPPDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109249-B2 | Composition containing a cross-linkable matrix precursor and a poragen, and porous matrix prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1141128-B1 | A COMPOSITION CONTAINING A CROSS-LINKABLE MATRIX PRECURSOR AND A PORAGEN, AND A POROUS MATRIX PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-04-12 | — | — | EP | disclosed |
| US-6887910-B2 | Composition containing a cross-linkable matrix precursor and a poragen, and a porous matrix prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050014855-A1 | Composition containing a cross-linkable matrix precursor and a poragen, and a porous matrix prepared therefrom | BRUZA KENNETH J (US) | 2005-01-20 | — | — | US | disclosed |
| US-6653358-B2 | Electronics; integrated circuits; containing benzocyclobutene polymer | DOW GLOBAL TECHNOLOGIES INC. | 2003-11-25 | — | — | US | disclosed |
| US-6630520-B1 | Matrix precursor comprises a material selected from cyclopentadienone and acetylene functional compounds, at least some of which have three or more reactive functional groups; partially polymerized reaction products and perfluoroethylenes | DOW GLOBAL TECHNOLOGIES INC. | 2003-10-07 | — | — | US | disclosed |
| US-20030092785-A1 | Composition containing a cross-linkable matrix precursor and a poragen, and a porous matrix prepared therefrom | BRUZA KENNETH J (US) | 2003-05-15 | — | — | US | disclosed |
| US-20030083392-A1 | Composition containing a cross-linkable matrix precursor and a poragen, and a porous matrix prepared therefrom | BRUZA KENNETH J (US) | 2003-05-01 | — | — | US | disclosed |
| EP-1141128-A1 | A COMPOSITION CONTAINING A CROSS-LINKABLE MATRIX PRECURSOR AND A PORAGEN, AND A POROUS MATRIX PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000031183-A1 | A COMPOSITION CONTAINING A CROSS-LINKABLE MATRIX PRECURSOR AND A PORAGEN, AND A POROUS MATRIX PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2000-06-02 | — | — | WO | disclosed |