Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077211 | 0.80 | IDO1 (0.30) | ALOX5 | |
| SCHEMBL5737091 | 0.76 | — | — | |
| SCHEMBL12199688 | 0.73 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL10442401 | 0.68 | — | — | |
| SCHEMBL21383118 | 0.68 | — | — | |
| SCHEMBL24265597 | 0.68 | MEN1 (0.31) | — | |
| SCHEMBL3074714 | 0.68 | HTR6 (0.30) | — | |
| SCHEMBL31301082 | 0.68 | — | — | |
| SCHEMBL3074983 | 0.68 | IDO1 (0.36) | — | |
| SCHEMBL3833168 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149442-A1 | Atypical antipsychotic agents having low affinity for the D2 receptor | KAPUR SHITIJ | 2009-06-11 | — | — | US | disclosed |
| US-20050222121-A1 | Atypical antipsychotic agents having low affinity for the D2 receptor | KAPUR SHITIJ | 2005-10-06 | — | — | US | disclosed |
| US-20020182594-A1 | Chemomagnetic retrieval of CMV and CMV infected cells | CHEMOCENTRYX (US) | 2002-12-05 | — | — | US | disclosed |
| US-20020127544-A1 | Modulators of US 28 | CHEMOCENTRYX | 2002-09-12 | — | — | US | disclosed |
| WO-2002062956-A2 | CHEMOMAGNETIC RETRIEVAL OF CMV AND CMV INFECTED CELLS | CHEMOCENTRYX, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
| WO-2002017900-A2 | MODULATORS OF US28 (CHEMOKINES) FOR TREATING CYTOMEGALOVIRUS INFECTIONS | CHEMOCENTRYX, INC. (US) | 2002-03-07 | — | — | WO | disclosed |
| EP-1181294-A1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | Sanochemia Pharmazeutika Aktiengesellschaft (AT) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001074820-A1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) | 2001-10-11 | — | — | WO | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149442-A1 | Atypical antipsychotic agents having low affinity for the D2 receptor | DRD2, OPRD1, GRIN2A | ALOX5 2393/4885 |
| US-20050222121-A1 | Atypical antipsychotic agents having low affinity for the D2 receptor | DRD2, OPRD1, GRIN2A | ALOX5 2393/4885 |
| US-20020127544-A1 | Modulators of US 28 | CCR8, CCL5, CXCL10 | ALOX5 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.