SCHEMBL4190519

SCHEMBL4190519

CC(CC1CCCCC1)NCc1ccncc1NC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 6/20 0.45
AOC1 P19801 5/20 0.40
AOC3 Q16853 5/20 0.40
CNR1 P21554 1/20 0.36
FPR2 P25090 1/20 0.36
GAA P10253 1/20 0.35
NPY5R Q15761 1/20 0.35
KDM6B O15054 1/20 0.35
PRMT3 O60678 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197451 0.91 KDM4C (0.42) KDM4CAOC1AOC3CNR1FPR2
SCHEMBL4192548 0.84 KMT2A (0.47) NPY5R
SCHEMBL4708769 0.79 KDM4C (0.40) KDM4CAOC1AOC3CNR1GAA
SCHEMBL4195445 0.79 REN (0.38) KDM4CCNR1FPR2GAAPRMT3
SCHEMBL4709150 0.78 KDM4C (0.40) KDM4CAOC1AOC3GAAKDM6B
SCHEMBL4194840 0.78 NPY5R (0.38) CNR1NPY5R
SCHEMBL4190351 0.78 MME (0.40) NPY5R
SCHEMBL4190624 0.78 CTSL (0.44) GAA
SCHEMBL4198225 0.78 CTSL (0.44) GAA
SCHEMBL4197332 0.78 CTSL (0.44) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 KDM4C 4153/4885AOC1 2876/4885AOC3 2980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.