SCHEMBL4197451

SCHEMBL4197451

CC(CC1CCCCC1)NCc1cnccc1NC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 4/20 0.42
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
FPR2 P25090 1/20 0.36
GAA P10253 1/20 0.35
NPY5R Q15761 1/20 0.35
F2RL1 P55085 1/20 0.35
AOC1 P19801 1/20 0.35
AOC3 Q16853 1/20 0.35
BRS3 P32247 1/20 0.35
PRMT3 O60678 1/20 0.35
LDLR P01130 2/20 0.35
PSMB11 A5LHX3 1/20 0.35
PSMA7 O14818 1/20 0.35
PSMB1 P20618 1/20 0.35
PSMA1 P25786 1/20 0.35
PSMA2 P25787 1/20 0.35
PSMA3 P25788 1/20 0.35
PSMA4 P25789 1/20 0.35
PSMB8 P28062 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4190519 0.91 KDM4C (0.45) KDM4CCNR1FPR2GAANPY5R
SCHEMBL4192548 0.84 KMT2A (0.47) NPY5RF2RL1SMN1; SMN2
SCHEMBL4708832 0.79 KDM4C (0.38) KDM4CCNR1CNR2GAANPY5R
SCHEMBL4201892 0.79 REN (0.38) KDM4CCNR1CNR2FPR2GAA
SCHEMBL4190351 0.78 MME (0.40) NPY5RSMN1; SMN2
SCHEMBL4194840 0.78 NPY5R (0.38) CNR1CNR2NPY5RF2RL1SMN1; SMN2
SCHEMBL4710745 0.78 GAA (0.38) KDM4CGAABRS3SMN1; SMN2
SCHEMBL4198225 0.78 CTSL (0.44) GAAF2RL1LDLR
SCHEMBL4190624 0.78 CTSL (0.44) GAAF2RL1LDLR
SCHEMBL4197332 0.78 CTSL (0.44) GAAF2RL1LDLR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 KDM4C 4153/4885CNR1 4619/4885CNR2 4811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.