Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710188 | 0.94 | LMNA (0.40) | RAB9AMAPTKMT2ALMNAMEN1 | |
| SCHEMBL4203402 | 0.91 | RAB9A (0.43) | RAB9AMAPTKMT2ALMNAMEN1 | |
| SCHEMBL4190547 | 0.91 | MAPK9 (0.39) | RAB9AMAPTKMT2ALMNAMEN1 | |
| Acetonitrile SCHEMBL7707450 | 0.90 | MAPK9 (0.38) | RAB9AMAPTKMT2ALMNAMEN1 | |
| SCHEMBL4201459 | 0.89 | LMNA (0.45) | RAB9AMAPTKMT2ALMNAMEN1 | |
| SCHEMBL4203404 | 0.88 | PTGS1 (0.36) | RAB9AMAPTKMT2ALMNAMEN1 | |
| SCHEMBL4197137 | 0.88 | MEN1 (0.41) | RAB9AMAPTKMT2ALMNAMEN1 | |
| SCHEMBL4197970 | 0.87 | GPX4 (0.35) | RAB9AMAPTKMT2ALMNAMEN1 | |
| SCHEMBL5613992 | 0.87 | PTGS1 (0.36) | RAB9AKMT2AMEN1NPC1MAPK1 | |
| SCHEMBL4197270 | 0.86 | PTGS1 (0.36) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | disclosed |