Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30666338 | 1.00 | NR4A2 (0.64) | NR4A2CA12CA1CA2CA6 | |
| SCHEMBL4186280 | 0.89 | HDAC3 (0.59) | NR4A2CA12CA1CA2CA6 | |
| SCHEMBL3943135 | 0.89 | HDAC1 (0.65) | NR4A2CA12CA1CA2CA6 | |
| Succinic Acid SCHEMBL8655758 | 0.83 | ALDH1A1 (0.60) | NR4A2CA12CA1CA2CA6 | |
| SCHEMBL14277039 | 0.83 | PARP1 (0.60) | NR4A2CA12CA1CA2CA6 | |
| SCHEMBL4569137 | 0.82 | PARP1 (0.59) | CA12CA1CA2CA6CA9 | |
| SCHEMBL2979252 | 0.82 | KDM4E (0.59) | CA12CA1CA2CA6CA9 | |
| SCHEMBL7668492 | 0.82 | CA12 (0.61) | CA12CA1CA2CA6CA9 | |
| SCHEMBL8535224 | 0.81 | SMN1; SMN2 (0.72) | NR4A2ALDH1A1CYP2C19GAACYP1A2 | |
| SCHEMBL2026598 | 0.81 | HSD17B3 (0.60) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109675550-B | Molybdenum-boron/sepiolite catalyst and preparation method and application thereof | 安徽理工大学 | 2021-10-26 | — | — | CN | claimed |
| CN-109369367-B | Method for preparing 4- (3-hydroxyphenyl) -4-oxobutyric acid from lignin | 安徽理工大学 | 2021-01-15 | — | — | CN | claimed |
| CN-109369367-A | A kind of lignin prepares 4-(3- hydroxy phenyl) method of -4- ketobutyric acid | 安徽理工大学 | 2019-02-22 | — | — | CN | claimed |
| CN-109675550-B | Molybdenum-boron/sepiolite catalyst and preparation method and application thereof | 安徽理工大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-109369367-B | Method for preparing 4- (3-hydroxyphenyl) -4-oxobutyric acid from lignin | 安徽理工大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-109369367-B | Method for preparing 4- (3-hydroxyphenyl) -4-oxobutyric acid from lignin | 安徽理工大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-109369367-B | Method for preparing 4- (3-hydroxyphenyl) -4-oxobutyric acid from lignin | 安徽理工大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-109675550-A | A kind of molybdenum-boron/sepiolite catalyst and its preparation method and application | 安徽理工大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-109369367-A | A kind of lignin prepares 4-(3- hydroxy phenyl) method of -4- ketobutyric acid | 安徽理工大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-109369367-A | A kind of lignin prepares 4-(3- hydroxy phenyl) method of -4- ketobutyric acid | 安徽理工大学 | 2019-02-22 | — | — | CN | disclosed |
| EP-2023930-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. Organon (NL) | 2009-02-18 | — | — | EP | disclosed |
| WO-2008020866-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON | 2008-02-21 | — | — | WO | disclosed |
| US-20070155707-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | KADMUS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| US-4082843-A | 3-(3-(3-Substituted amino-2-hydroxypropoxy)phenyl)-6-hydrazino pyridazines and their use as vasodilators and β-adrenergic blocking agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-04-04 | — | — | US | disclosed |
| US-4058529-A | Polycyclic amino derivatives of pyrrolidone and piperidone | CIBA-GEIGY CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-4011321-A | 6-(3-SUBSTITUTED AMINO-2-HYDROXYPROPOXYARYL)-4,5-DIHYDRO-3(2H)-PYRIDAZINONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155707-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, NAAA | NR4A2 3076/4885CA12 1457/4885CA1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.