Pantoprazole

Pantoprazole

SCHEMBL4192305

COc1ccnc(C[S@+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)c1OC

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 14/20 0.54
ATP4B P51164 14/20 0.54
CYP2C9 P11712 2/20 0.54
KDM4E B2RXH2 1/20 0.54
SLC22A2 O15244 1/20 0.54
DDAH1 O94760 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
ABCB1 P08183 1/20 0.54
CYP3A4 P08684 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54
ADRA1A P35348 1/20 0.54
FASN P49327 1/20 0.54
SLC47A2 Q86VL8 1/20 0.54
SLC47A1 Q96FL8 1/20 0.54
ABCG2 Q9UNQ0 1/20 0.54
ATP1A1 P05023 7/20 0.45
ATP1B1 P05026 7/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pantoprazole SCHEMBL6469440 1.00 ATP4A (0.54) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL4942069 1.00 ATP4A (0.54) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL29465 1.00 ATP4A (0.54) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL29425016 1.00 ATP4A (0.54) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL12662938 1.00 ATP4A (0.54) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL1716777 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL6262319 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL4320242 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL1994484 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL3716300 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001866-B2 Burkholderia and applications thereof JIANGSU AOSAIKANG PHARMACEUTICAL CO., LTD. (CN) 2021-05-11 US claimed
US-20200385770-A1 BURKHOLDERIA AND APPLICATIONS THEREOF JIANGSU AOSAIKANG PHARMACEUTICAL CO., LTD. (CN) 2020-12-10 US claimed
US-20080234326-A1 Novel Salts of Pantoprazole and (S) - Pantoprazole ALTANA PHARMA AG (DE) 2008-09-25 US claimed
EP-1711179-A2 CALCIUM, POTASSIUM, ZINC, LITHIUM AND ALUMINIUM SALTS OF PANTOPRAZOLE AND (S)-PANTOPRAZOLE Altana Pharma AG (DE) 2006-10-18 EP claimed
US-20050288334-A1 Process for preparing optically pure active compounds ALTANA PHARMA AG (DE) 2005-12-29 US claimed
EP-1578742-A1 PROCESS FOR PREPARING OPTICALLY PURE ACTIVE COMPOUNDS ALTANA Pharma AG (DE) 2005-09-28 EP claimed
WO-2005074929-A2 CALCIUM, POTASSIUM, ZINC, LITHIUM AND ALUMINIUM SALTS OF PANTOPRAZOLE AND (S)-PANTOPRAZOLE ALTANA PHARMA AG (DE) 2005-08-18 WO claimed
WO-2004052882-A1 PROCESS FOR PREPARING OPTICALLY PURE ACTIVE COMPOUNDS ALTANA PHARMA AG (DE) 2004-06-24 WO claimed
US-20220202796-A1 CXCL10 Inhibitors LAPKO INC, dba AFECTA PHARMACEUTICALS 2022-06-30 US disclosed
US-20210338650-A1 CXCL10 Inhibitors AFECTA PHARMACEUTICALS, INC. (US) 2021-11-04 US disclosed
US-11001866-B2 Burkholderia and applications thereof JIANGSU AOSAIKANG PHARMACEUTICAL CO., LTD. (CN) 2021-05-11 US disclosed
US-11001866-B2 Burkholderia and applications thereof JIANGSU AOSAIKANG PHARMACEUTICAL CO., LTD. (CN) 2021-05-11 US disclosed
EP-3380085-B1 ORAL PREPARATIONS WITH OMEPRAZOLE OR PANTOPRAZOLE SYMRISE AG (DE) 2021-01-13 EP disclosed
US-20200385770-A1 BURKHOLDERIA AND APPLICATIONS THEREOF JIANGSU AOSAIKANG PHARMACEUTICAL CO., LTD. (CN) 2020-12-10 US disclosed
US-20120197021-A1 OPTICAL RESOLUTION OF SUBSTITUTED 2-(2-PYRIDINYLMETHYLSULPHINYL)-1H-BENZIMIDAZOLES HETERO RESEARCH FOUNDATION (IN) 2012-08-02 US disclosed
US-20120197021-A1 OPTICAL RESOLUTION OF SUBSTITUTED 2-(2-PYRIDINYLMETHYLSULPHINYL)-1H-BENZIMIDAZOLES HETERO RESEARCH FOUNDATION (IN) 2012-08-02 US disclosed
WO-2011042910-A2 OPTICAL RESOLUTION OF SUBSTITUTED 2-(2- PYRIDINYLMETHYLSULPHINYL)-1H-BENZIMIDAZOLES HETERO RESEARCH FOUNDATION (IN) 2011-04-14 WO disclosed
WO-2009147178-A2 NOVEL MEDICAL USE OF SUBSTITUTED PYRIDIN-2-YLMETHYLSULPHINYL-1H-BENZIMIDAZOLES NYCOMED GMBH (DE) 2009-12-10 WO disclosed
EP-1711179-A2 CALCIUM, POTASSIUM, ZINC, LITHIUM AND ALUMINIUM SALTS OF PANTOPRAZOLE AND (S)-PANTOPRAZOLE Altana Pharma AG (DE) 2006-10-18 EP disclosed
WO-2005074929-A2 CALCIUM, POTASSIUM, ZINC, LITHIUM AND ALUMINIUM SALTS OF PANTOPRAZOLE AND (S)-PANTOPRAZOLE ALTANA PHARMA AG (DE) 2005-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202796-A1 CXCL10 Inhibitors CXCL10, CCL5, CCL11 ATP4A 4581/4885ATP4B 4629/4885CYP2C9 4152/4885
US-20120197021-A1 OPTICAL RESOLUTION OF SUBSTITUTED 2-(2-PYRIDINYLMETHYLSULPHINYL)-1H-BENZIMIDAZOLES BRI3BP, HRH2, BRPF1 ATP4A 595/4885ATP4B 1246/4885CYP2C9 598/4885
US-20210338650-A1 CXCL10 Inhibitors CXCL10, CCL5, CCL11 ATP4A 4581/4885ATP4B 4629/4885CYP2C9 4152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.