Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | F2 | P00734 | 3/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.60 |
| ▸ | SCN1A | P35498 | 2/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30442076 | 1.00 | CA2 (0.62) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL8328504 | 0.87 | NSD2 (0.52) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL28265953 | 0.85 | CASP1 (0.51) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL6580093 | 0.83 | CA1 (0.61) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL10991218 | 0.83 | LDHA (0.47) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL6006634 | 0.81 | CYP3A4 (0.69) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL1427884 | 0.80 | CA1 (0.48) | CA2CA1CA9CYP2C9HTR6 | |
| SCHEMBL8224014 | 0.80 | F2 (0.60) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL2371351 | 0.80 | CA1 (0.57) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL10994471 | 0.80 | CA1 (0.57) | CA2CA1CA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105355-A | A kind of preparation method of 1,2,3- triazole-[1,5-a] and quinolines | 烟台大学 | 2019-08-09 | — | — | CN | claimed |
| CN-103396464-A | Preparation method of ivermectin | HEBEI VEYON ANIMAL PHARMACEUTICAL CO LTD | 2013-11-20 | — | — | CN | claimed |
| CN-102101948-A | Ammonia-releasing, nitrogen-releasing, acid-producing foaming dissolution inhibitor/promoter for thermosensitive computer to plate (CTP) plate, and preparation method and use thereof | WEIHAI ECONOMIC ZONE TIANCHENG CHEMICAL AND ENGINEERING CO LTD | 2011-06-22 | — | — | CN | claimed |
| CN-1138458-A | Treatment and prevention of prostatic cancer | LILLY CO ELI (US) | 1996-12-25 | — | — | CN | claimed |
| EP-0103840-B1 | METHOD FOR PREPARING 1,2,3-TRIHETERO 5-MEMBERED HETEROCYCLIC COMPOUNDS | LEDERLE (JAPAN) LTD. (JP) | 1987-03-04 | — | — | EP | claimed |
| US-4540794-A | Method for preparing 5-mercapto-1,2,3-thiadiazole salts | LEDERLE (JAPAN), LTD. (JP) | 1985-09-10 | — | — | US | claimed |
| EP-0103840-A2 | Method for preparing 1,2,3-trihetero 5-membered heterocyclic compounds | LEDERLE (JAPAN) LTD. (JP) | 1984-03-28 | — | — | EP | claimed |
| CN-114411178-B | Polysubstituted pyrazole compound and electrochemical synthesis method thereof | 南京工业大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-111995620-B | Preparation method of 1,3, 4-thiadiazole compound and compound prepared by same | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-112341376-B | Preparation method of cycloolefine amine sulfone derivative | 温州医科大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-109232420-B | Method for synthesizing 6-sulfone methyl phenanthridine derivatives through visible light catalysis | 上饶师范学院 | 2021-12-24 | — | — | CN | disclosed |
| CN-110105355-B | Preparation method of 1,2, 3-triazole- [1,5-a ] quinoline compound | 烟台大学 | 2021-09-21 | — | — | CN | disclosed |
| US-4525487-A | FROM USATURATED POLYESTER SULFONYL HYDRAZIDE, PROMOTER, CATALYST, AND QATERNARY AMMONIUM SALT | UNIROYAL, INC. (US) | 1985-06-25 | — | — | US | disclosed |
| US-4521542-A | Arylsulphonyl hydrazones as blowing agents | BAYER AKTIENGESELLSCHAFT (DE) | 1985-06-04 | — | — | US | disclosed |
| EP-0103840-A2 | Method for preparing 1,2,3-trihetero 5-membered heterocyclic compounds | LEDERLE (JAPAN) LTD. (JP) | 1984-03-28 | — | — | EP | disclosed |
| EP-0101197-A2 | Method for preparing foam using cobalt/potassium promoters | UNIROYAL, INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4401771-A | HYDROCARBYLSULFONYL HYDRAZIDE FOAMING AGENT | UNIROYAL, INC. (US) | 1983-08-30 | — | — | US | disclosed |
| US-4327196-A | USING SULFONYL HYDRAZIDE BLOWING AGENTS, PEROXIDE CURING AGENTS FOR SIMULTANEOUS FOAMING AND CURING | UNIROYAL, INC. (US) | 1982-04-27 | — | — | US | disclosed |
| EP-0034201-A1 | Method and composition for making foamed crosslinked polyethylene | Argus Chemical Corporation (US) | 1981-08-26 | — | — | EP | disclosed |