Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580093 | 0.83 | CA1 (0.61) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL1756801 | 0.82 | F2 (0.54) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL11479510 | 0.81 | F2 (0.57) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL419323 | 0.80 | CA2 (0.62) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL10994471 | 0.80 | CA1 (0.57) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL3698223 | 0.80 | HCRTR1 (0.58) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL2371351 | 0.80 | CA1 (0.57) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL30442076 | 0.80 | CA2 (0.62) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL9180166 | 0.79 | TSHR (0.59) | F2PRSS1PRSS2PRSS3HCRTR1 | |
| SCHEMBL20446636 | 0.79 | F2 (0.55) | F2PRSS1PRSS2PRSS3HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103224503-A | Novel method for compounding naphtho-spirooxazine type photochromic compound | UNIV CENTRAL SOUTH | 2013-07-31 | — | — | CN | claimed |
| CN-115667404-A | Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device | 富士胶片株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-115190891-A | Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device | 富士胶片株式会社 | 2022-10-14 | — | — | CN | disclosed |
| CN-114514470-A | Pattern forming method, photosensitive resin composition, method for manufacturing laminate, and method for manufacturing semiconductor device | 富士胶片株式会社 | 2022-05-17 | — | — | CN | disclosed |
| CN-114341731-A | Method for producing cured film, photocurable resin composition, method for producing laminate, and method for producing semiconductor device | 富士胶片株式会社 | 2022-04-12 | — | — | CN | disclosed |
| US-20210053915-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | THE JOHNS HOPKINS UNIVERSITY | 2021-02-25 | — | — | US | disclosed |
| US-10829445-B2 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190144380-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | THE JOHNS HOPKINS UNIVERSITY | 2019-05-16 | — | — | US | disclosed |
| US-10179765-B2 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-9969684-B2 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20140336396-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2014-11-13 | — | — | US | disclosed |
| US-20140336396-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2014-11-13 | — | — | US | disclosed |
| CN-103224503-A | Novel method for compounding naphtho-spirooxazine type photochromic compound | UNIV CENTRAL SOUTH | 2013-07-31 | — | — | CN | disclosed |
| US-20110306614-A1 | N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-12-15 | — | — | US | disclosed |
| US-20110306614-A1 | N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-12-15 | — | — | US | disclosed |
| US-8030356-B2 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-8030356-B2 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-20070299107-A1 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | NATIONAL SCIENCE FOUNDATION | 2007-12-27 | — | — | US | disclosed |
| US-20070299107-A1 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | NATIONAL SCIENCE FOUNDATION | 2007-12-27 | — | — | US | disclosed |
| WO-2007109175-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306614-A1 | N-Hydroxylsulfonamide Derivatives as New Physiologically Useful Nitroxyl Donors | TNNI3, TNNC1, NME4 | F2 4071/4885PRSS1 1821/4885PRSS2 2556/4885 |
| US-20210053915-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | TNNI3, TNNC1, TNNT2 | F2 4009/4885PRSS1 1780/4885PRSS2 2430/4885 |
| US-10829445-B2 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | TNNI3, TNNC1, TNNT2 | F2 4009/4885PRSS1 1780/4885PRSS2 2430/4885 |
| US-20190144380-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | TNNI3, TNNC1, TNNT2 | F2 4009/4885PRSS1 1780/4885PRSS2 2430/4885 |
| US-20070299107-A1 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | TNNI3, TNNC1, NME4 | F2 4071/4885PRSS1 1821/4885PRSS2 2556/4885 |
| US-10179765-B2 | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors | TNNI3, TNNC1, TNNT2 | F2 4009/4885PRSS1 1780/4885PRSS2 2430/4885 |
| US-20140336396-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | TNNI3, TNNC1, NME4 | F2 4071/4885PRSS1 1821/4885PRSS2 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.