Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10256352 | 0.95 | TSHR (0.50) | TSHRLMNAALDH1A1APEX1MEN1 | |
| SCHEMBL16979675 | 0.91 | TSHR (0.42) | TSHRLMNAALDH1A1APEX1MEN1 | |
| SCHEMBL16271537 | 0.85 | TSHR (0.38) | TSHRLMNAALDH1A1APEX1MEN1 | |
| SCHEMBL19627553 | 0.85 | BBOX1 (0.41) | TSHRLMNAALDH1A1APEX1FFAR3 | |
| SCHEMBL16271556 | 0.85 | TSHR (0.38) | TSHRLMNAALDH1A1APEX1MEN1 | |
| SCHEMBL3257954 | 0.84 | TSHR (0.41) | TSHRLMNAALDH1A1APEX1MEN1 | |
| SCHEMBL235857 | 0.80 | TSHR (0.65) | TSHRLMNAALDH1A1APEX1FFAR3 | |
| SCHEMBL20437635 | 0.79 | LMNA (0.39) | TSHRLMNAALDH1A1APEX1MEN1 | |
| Oxibetaine SCHEMBL9243808 | 0.79 | TSHR (0.50) | TSHRLMNAALDH1A1APEX1MEN1 | |
| SCHEMBL16271550 | 0.77 | TGFBR1 (0.33) | TSHRLMNAALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719768-B1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | ASAHI KASEI PHARMA CORP (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-20120015925-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| US-7973030-B2 | Benzothiazepine and benzothiepine compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20090042274-A1 | Method of Purifying Virus Envelope | GENOMIDEA INC. (JP) | 2009-02-12 | — | — | US | disclosed |
| US-7312208-B2 | Quaternary ammonium compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | ASHAI KASEI PHARAMA CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1783138-A1 | METHOD OF PURIFYING VIRUS ENVELOPE | GenomIdea Inc. (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-0649834-A1 | Carboxybetaine and sulfobetaine and detergent composition and cosmetic containing the same | KAO CORPORATION (JP) | 1995-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015925-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | SLC10A1, SREBF1, SPTLC1 | TSHR 3208/4885LMNA 1909/4885ALDH1A1 1261/4885 |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | SLC10A1, GOT1, CES1 | TSHR 2972/4885LMNA 2785/4885ALDH1A1 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.