SCHEMBL4193873

SCHEMBL4193873

Cc1ccc(-c2cc(-c3ccccc3)c(CC#N)c(-c3ccc(C)cc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.49
HPGD P15428 4/20 0.43
ADORA1 P30542 3/20 0.43
KDM4E B2RXH2 3/20 0.43
ADORA2A P29274 2/20 0.43
PPARG P37231 1/20 0.43
NCOA2 Q15596 1/20 0.43
NCOA1 Q15788 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.43
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
NTSR1 P30989 1/20 0.41
PTGS1 P23219 1/20 0.39
RCE1 Q9Y256 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5380662 0.77 LMNA (0.42) HPGDKDM4EALDH1A1GALR3GAA
SCHEMBL28097482 0.74 HPRT1 (0.53) HPRT1HPGDKDM4EMEN1KMT2A
Water SCHEMBL1929109 0.74 HPGD (0.50) HPRT1HPGDADORA1KDM4EADORA2A
Water SCHEMBL312989 0.74 HPGD (0.50) HPRT1HPGDADORA1KDM4EADORA2A
SCHEMBL7013171 0.74 HTR7 (0.42) HPGDADORA1KDM4EADORA2APPARG
SCHEMBL9486287 0.73 DPP4 (0.40) HPGDADORA1KDM4EADORA2APPARG
SCHEMBL18412131 0.72 MEN1 (0.57) HPRT1HPGDKDM4EMEN1KMT2A
SCHEMBL29688196 0.72 LMNA (0.53) HPRT1HPGDKDM4EMEN1KMT2A
SCHEMBL22104835 0.72 MEN1 (0.57) HPRT1HPGDKDM4EMEN1KMT2A
SCHEMBL3294988 0.72 LMNA (0.53) HPRT1HPGDKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592475-B2 includes the organic substance in the state of powder, liquid and film with the stilbene core structure and the terminal branched phenyl structure e.g. [1,3-bis(4-methyl-phenyl)-5-(4-cyanomethyl-phenyl)]-benzene; high luminescent efficiency; useful to the organic electroluminescence display DONGWOO FINE-CHEM CO., LTD. (KR) 2009-09-22 US disclosed
US-20090014686-A1 Novel branched alpha-cyanostilbene fluorophores PARK SOOYOUNG 2009-01-15 US disclosed
US-20070149799-A1 Novel branched alpha-cyanostilbene fluorophores SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090014686-A1 Novel branched alpha-cyanostilbene fluorophores EBPL, OCIAD1, TTL HPRT1 3390/4885HPGD 1440/4885ADORA1 3512/4885
US-20070149799-A1 Novel branched alpha-cyanostilbene fluorophores EBPL, OCIAD1, TTL HPRT1 3390/4885HPGD 1440/4885ADORA1 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.