Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13385994 | 0.81 | LMNA (0.44) | DPP4HPGDALDH1A1PDCD1CD274 | |
| SCHEMBL29018975 | 0.81 | MMP3 (0.44) | DPP4KDM4EHPGDALDH1A1KMT2A | |
| SCHEMBL7013171 | 0.80 | HTR7 (0.42) | DPP4CA12CA1CA2CA7 | |
| SCHEMBL28393638 | 0.79 | ALOX5 (0.53) | DPP4HPGDALDH1A1ADORA1MEN1 | |
| SCHEMBL15456146 | 0.79 | ADRA2C (0.45) | HTR7HPGDALDH1A1PDCD1CD274 | |
| SCHEMBL1343377 | 0.79 | DPP4 (0.56) | DPP4HTR7HPGDALDH1A1PDCD1 | |
| SCHEMBL9485214 | 0.78 | PDCD1 (0.53) | DPP4CA12CA1CA2CA7 | |
| SCHEMBL18569389 | 0.78 | PTGDR2 (0.46) | DPP4CA12CA1CA2CA7 | |
| SCHEMBL10092813 | 0.77 | HDAC7 (0.41) | DPP4CA12CA1CA2CA7 | |
| SCHEMBL3786898 | 0.77 | DPP4 (0.59) | DPP4CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243054-A | Hypotensive agents, cardiovascular disorders or nervous system disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-07 | — | — | US | disclosed |