SCHEMBL4194935

SCHEMBL4194935

CC(CC1CCCCC1)NCc1cccnc1OC(=O)Nc1cc2ccccc2s1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
REN P00797 1/20 0.35
OPRM1 P35372 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GCK P35557 4/20 0.33
HPGD P15428 2/20 0.33
GAA P10253 1/20 0.33
RECQL P46063 1/20 0.33
HTR1A P08908 1/20 0.33
DRD2 P14416 1/20 0.33
HTR2A P28223 1/20 0.33
METAP2 P50579 2/20 0.33
METAP1 P53582 2/20 0.33
CTSK P43235 1/20 0.32
RIPK1 Q13546 1/20 0.32
NPY5R Q15761 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4190568 0.88 GCK (0.37) RENOPRM1MEN1KMT2AKDM4E
SCHEMBL4707716 0.87 GCK (0.35) RENOPRM1MEN1KMT2AKDM4E
SCHEMBL4190961 0.86 HTR1A (0.37) RENOPRM1MEN1KMT2AKDM4E
SCHEMBL4197246 0.85 REN (0.36) RENOPRM1MEN1KMT2AKDM4E
SCHEMBL4186546 0.85 REN (0.36) RENOPRM1MEN1KMT2AKDM4E
SCHEMBL4707023 0.84 OPRM1 (0.39) OPRM1MEN1KMT2AKDM4ENPC1
SCHEMBL4190982 0.83 HTR1A (0.36) OPRM1MEN1KMT2AKDM4EHTR1A
SCHEMBL4194046 0.82 HTR1A (0.36) RENOPRM1MEN1KMT2AKDM4E
SCHEMBL4707353 0.81 CNR1 (0.36) RENOPRM1MEN1KMT2AKDM4E
SCHEMBL4195445 0.78 REN (0.38) RENOPRM1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 REN 4111/4885OPRM1 2434/4885MEN1 3776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.